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Genomic landscape of paediatric adrenocortical tumours

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  1. Article

    Open Access

    NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia

    Non-T cell activation linker (NTAL) is a lipid raft-membrane protein expressed by normal and leukemic cells and involved in cell signaling. In acute promyelocytic leukemia (APL), NTAL depletion from lipid raft...

    Carolina Hassibe Thomé, Germano Aguiar Ferreira… in Scientific Reports (2020)

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  2. Article

    Open Access

    A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML

    Improvement in survival has been achieved for children and adolescents with AML but is largely attributed to enhanced supportive care as opposed to the development of better treatment regimens. High risk subty...

    Christina D. Drenberg, Anang Shelat, **jun Dang, Anitria Cotton… in Nature Communications (2019)

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  3. Article

    Open Access

    The genomic landscape of pediatric myelodysplastic syndromes

    Myelodysplastic syndromes (MDS) are uncommon in children and have a poor prognosis. In contrast to adult MDS, little is known about the genomic landscape of pediatric MDS. Here, we describe the somatic and ger...

    Jason R. Schwartz, **g Ma, Tamara Lamprecht, Michael Walsh… in Nature Communications (2017)

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