8 Result(s)
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Article
Open AccessMap** anhedonia-specific dysfunction in a transdiagnostic approach: an ALE meta-analysis
Anhedonia is a prominent symptom in neuropsychiatric disorders, most markedly in major depressive disorder (MDD) and schizophrenia (SZ). Emerging evidence indicates an overlap in the neural substrates of anhed...
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Article
Neuroanatomical Prediction of Anhedonia in Adolescents
Anhedonia is a transdiagnostic risk factor implicated in mental illness onset, treatment non-response, and suicidal behaviors. Prior cross-sectional research in adults has shown that anhedonia is associated wi...
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Article
Abnormal frontoinsular-default network dynamics in adolescent depression and rumination: a preliminary resting-state co-activation pattern analysis
Clinical depression commonly emerges in adolescence, which is also a time of develo** cognitive ability and related large-scale functional brain networks implicated in depression. In depressed adults, abnorm...
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Article
Dissociating default mode network resting state markers of suicide from familial risk factors for depression
Neural signatures of suicide risk likely reflect a combination of specific and non-specific factors, and clarifying specific factors may facilitate development of novel treatments. Previously, we demonstrated ...
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Anhedonia and Suicide
Suicide is a leading cause of death, and presently, there is no definitive clinical indicator of future suicide behaviors. Anhedonia, a transdiagnostic symptom reflecting diminished ability to experience pleas...
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Open AccessReducing default mode network connectivity with mindfulness-based fMRI neurofeedback: a pilot study among adolescents with affective disorder history
Adolescents experience alarmingly high rates of major depressive disorder (MDD), however, gold-standard treatments are only effective for ~50% of youth. Accordingly, there is a critical need to develop novel i...
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Article
Open AccessNeural sensitivity following stress predicts anhedonia symptoms: a 2-year multi-wave, longitudinal study
Animal models of depression show that acute stress negatively impacts functioning in neural regions sensitive to reward and punishment, often manifesting as anhedonic behaviors. However, few human studies have...
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Article
Open AccessWhy do adolescents attempt suicide? Insights from leading ideation-to-action suicide theories: a systematic review
Suicide is a leading cause of death among adolescents, and recent suicide theories have sought to clarify the factors that facilitate the transition from suicide ideation to action. Specifically, the Interpers...
