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within Rainer Claus Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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  1. Article

    Open Access

    PRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood-derived hematopoietic stem and progenitor cells

    Cord blood hematopoietic stem cells (CB-HSCs) are an outstanding source for transplantation approaches. However, the amount of cells per donor is limited and culture expansion of CB-HSCs is accompanied by a lo...

    Linda Varagnolo, Qiong Lin, Nadine Obier, Christoph Plass… in Scientific Reports (2015)

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  2. Article

    Open Access

    RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia

    Juvenile myelomonocytic leukemia (JMML) is an aggressive myeloproliferative disorder of early childhood characterized by mutations activating RAS signaling. Established clinical and genetic markers fail to ful...

    Daniel B. Lipka, Tania Witte, Reka Toth, **g Yang… in Nature Communications (2017)

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