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  1. Article

    Open Access

    EPLIN: a fundamental actin regulator in cancer metastasis?

    Treatment of malignant disease is of paramount importance in modern medicine. In 2012, it was estimated that 162,000 people died from cancer in the UK which illustrates a fundamental problem. Traditional treat...

    Ross J. Collins, Wen G. Jiang, Rachel Hargest in Cancer and Metastasis Reviews (2015)

  2. Article

    Open Access

    WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-γ pathways

    It has recently been shown that WISP proteins (Wnt-inducted secreted proteins), a group of intra- and extra-cellular regulatory proteins, have been implicated in the initiation and progression of a variety of ...

    Jiafu Ji, Shuqin Jia, Yongning Jia, Ke Ji, Rachel Hargest in British Journal of Cancer (2015)

  3. Article

    Open Access

    Implication of metastasis suppressor gene, Kiss-1 and its receptor Kiss-1R in colorectal cancer

    Kiss-1 and Kiss-1R have been suggested as a novel pair of metastasis suppressors for several human solid tumours, however, their role in colorectal cancer remains largely unknown. Therefore, the aim of this st...

    Ke Ji, Lin Ye, Fiona Ruge, Rachel Hargest, Malcolm D Mason, Wen G Jiang in BMC Cancer (2014)