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    Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome

    Epigenetic mechanisms underlying tumorigenesis have recently received much attention as potential therapeutic targets of human cancer. We designed a pilot study to target DNA methylation and histone deacetylat...

    P Maslak, S Chanel, L H Camacho, S Soignet, P P Pandolfi, I Guernah, R Warrell… in Leukemia (2006)