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Substrate inhibition of adenosine phosphorylation in adenosine deaminase deficiency and adenosine-mediated inhibition of PP-ribose-P dependent nucleotide synthesis in hypoxanthine phosphoribosyltransferase deficient erythrocytes

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  1. Article

    RESPIRATORY SYNCYTIAL VIRUS (RSV) ENHANCES THE EXPRESSION OF ANTIGEN PRESENTING MOLECULES, ACCESSORY LIGANDS AND POLYMERIC IMMUNOGLOBULIN RECEPTOR BY UPPER AIRWAY EPITHELIUM. • 48

    R Garofalo, T Saito, R. W Deskin, V. E Reyes, R. M Goldblum, T Elliot in Pediatric Research (1996)

  2. Article

    923 GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY, NEUTROPHIL DYSFUNCTION AND CHROMOBACTERIUM VIOLACEUM SEPSIS

    A three year old white male with Class I glucose-6-phosphate dehydrogenase (G-6-PD) deficiency developed fever and lethargy. In spite of antibiotics, he developed septic shock and died twelve hours later. Bloo...

    R J Mamlok, C W Daeschner III, C G Mills, F C Schmalstieg in Pediatric Research (1985)

  3. Article

    PERSISTENCE OF IMMUNOLOGIC FACTORS FROM HUMAN MILK IN THE INTESTINAL TRACT OF VERY LOW BIRTH WEIGHT INFANTS

    The use of banked human milk for premature infants is frequently based on the potential importance of its immunologic components. We therefore examined the persistence of some immunologic factors from human mi...

    R M Goldblum, R J Schanler, C Garza, A S Goldman in Pediatric Research (1984)

  4. Article

    STRUCTURAL BASIS FOR THE MULTIPLE FUNCTIONS OF SECRETORY COMPONENT

    Secretory component (SC) plays a central role in the mucosal immune system. This polypeptide serves as the epithelial cell receptor and transporter for polymeric IgA (pIgA) and protects IgA from proteolysis. T...

    R M Goldblum, C S Woodard, J B Splawski, R M Denney in Pediatric Research (1984)

  5. Article

    RAPID DEVELOPMENT OF INFANTS POLYMERIC IgA IN THE SERUM OF INFANTS

    Three molecular forms of IgA, monomeric (mIgA), polymeric (pIgA), and secretory (sIgA) make up approximately 85,15, and 1% of the IgA in adult serum. IgA concentration in secretions (sIgA) increases with age m...

    J B Splawski, C S Woodard, R M Denney, R M Goldblum in Pediatric Research (1984)

  6. Article

    699 QUANTITATIVE MICROIMMUNOASSAY FOR IMMUNO-GLOBULIN CLASS SPECIFIC HUMAN ANTIBODIES

    In order to evaluate antibody responses in immunodeficient patients, we have developed a modification of the enzyme linked immunosorbent assay (ELISA) which is 1) sensitive, 2) specific for immunoglobulin clas...

    R M Goldblum, J T Howell, L T Moy in Pediatric Research (1978)

  7. Article

    LYMPHOCYTE MOTILITY IN CHRONIC LYMPHOCYTIC LEUKEMIA(CLL)AND X-UNKED HYPO-M-GLOBULINEMIA

    We have found that circulating human T lymphocytes are motile, whereas unstimulated B lymphocytes are not (RES, J.Reticuloendothel.Soc.20:331, 1976). Since motility is a functional morphologic marker of normal...

    A S Goldman, F C Schmolstieg, H B Rudloff, R M Goldblum, J B Alperin in Pediatric Research (1977)

  8. Article

    EFFECT OF RBC TRANSFUSIONS ON ADENOSINE DEAMINASE(ADA) DEFICIENT SEVERE COMBINED IMMUNODEFICIENCY(SCID)

    Previous work suggests that the immunological defect in ADA deficient SCID is mediated by increased lymphocyte nucleotides including ATP and cAMP. We attempted to improve this tmmunological deficit in a 10-mon...

    F C Schmalstieg, R M Goldblum, G C Mills, L T May, A S Goldman in Pediatric Research (1977)

  9. Article

    QUANTITATIVE IMMUNOSORBE NT ASSAY FOR SlgA

    Studies of the secretory immune system have been hampered by the lack of an assay to specifically measure SIgA in secretions which also contain serum IgA and free secretory componet (FSC). We have developed an...

    J H Von Bovel, R M Goldblum, F C Schmolstleg, A S Goldman in Pediatric Research (1977)