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Article
European Association for the study of Diabetes First Annual Meeting, Montecatini Terme, 20. IV.-22.IV. 1965
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Chapter
The Treatment of Diabetic Retinopathy by Pituitary Ablation
Since insulin became available, the life of the diabetic has become dramatically prolonged, but also bedevilled by the problem of diabetic complications. The most serious of these is the microangiopathy which ...
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Article
Die Auswirkung der sekundären Nebennierenrindeninsuffizienz auf Körperwasser und austauschbare Elektrolyte
Total body water, extracellular fluid volume, NaE and KE were measured with3H2O,77Br,24Na and43K in 5 patients with confirmed adrenocortical insufficiency before and after withdrawal of a maintenance dose of 7.5 ...
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Chapter and Conference Paper
The Relationship Between the Plasma Concentrations of Renin and Angiotensin with Total Exchangeable Sodium in Hypertension
That the renin-angiotensin system is involved in the pathogenesis of clinical hypertension, at least in some cases, is suggested particularly by studies of the type illustrated in Fig. 1. The data shown in thi...
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Article
Lipoprotein size distributions from the analytical ultracentrifugation of serum and lipoprotein samples
A FORTRAN computer program is presented for the reduction to a lipoprotein size distribution of data from the analytical ultracentrifugal analysis of total low density lipoproteins at a density of 1·0.63 g/ml....
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Chapter
Mineralocorticoids and sodium transport
Such is the wealth of information available on the mechanisms of action of hormones at the molecular level that it is easy to forget that most, if not all, of it has been gleaned during the last 20 years. It n...
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Chapter and Conference Paper
Artifacts in the Diagnosis of Essential Hypertension
Apart from increased arterial pressure, essential hypertension is a disease characterized by negative features. Diagnosis is reached by excluding conditions with positive features, Conn’s syndrome, renal arter...
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Chapter and Conference Paper
Is Idiopathic Hyperaldosteronism a Variant of Essential Hypertension or of Conn’s Syndrome?
Primary hyperaldosteronism, or Conn’s syndrome, results from an aldosterone-producing adenoma of the adrenal cortex. It presents with features of mineralocorticoid excess — increased secretion of aldosterone, ...
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Chapter
Mill’s Disease Amongst Medical Specialists in Hypertension
This remarkable statement is attributed to John Stuart Mill, the Nineteenth Century political economist [20]. The idea deserves wider currency. It is certainly relevant to the ways in which 20th Century doctor...
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Chapter
Sodium and Blood Pressure in Human Hypertension
The role of sodium in the pathogenesis of hypertension is not agreed. It is likely that excess dietary sodium or excessive retention of sodium is capable of raising blood pressure in some circumstances in man....
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Article
An LDV system for turbulence length scale measurements
An LDV system for making spatial correlation measurements of velocity fluctuations in turbulent nonreacting and reacting flows is presented. The LDV system is the dual beam type and consists of an elongated pr...
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Article
In vivo and in vitro studies of the site of inhibitory action of omeprazole on adrenocortical steroidogenesis
The site of omeprazole inhibition of adrenal steroidogenesis has been sought in vivo by analyzing the patterns of urinary steroid metabolite excretion after 6 days of treatment with placebo/omeprazole.
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Chapter and Conference Paper
Abstracts
Recent advances in laboratory diagnostic technology has shifted from classical procedures such as serum neutralization and complement fixation, to procedures that are more rapid, specific, sensitive and genera...
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Article
The anti-diabetogenic effect of essential fatty acid deficiency in multiple low-dose streptozotocin-treated mice persists if essential fatty acid repletion occurs outside of a brief window of susceptibility
We have previously shown that essential fatty acid deficiency prevents diabetes mellitus and ameliorates insulitis in multiple low-dose streptozotocin-treated male CD-1 mice and that repletion with 99% pure me...
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Article
Disordered gastric motor function in diabetes mellitus
The application of novel investigative techniques has demonstrated that disordered gastric motility occurs frequently in diabetes mellitus. Gastric emptying is abnormal in about 50% of diabetic patients and de...
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Chapter
Analysis of corticosteroids, corticosteroid metabolites and related compounds in body fluids and tissues
The adrenal cortex is the source of a number of steroid hormones which play a fundamental role in body metabolism. The elucidation of the complicated biosynthetic pathways and the metabolic fate of these hormo...
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Article
Effects of the glucocorticoid antagonist RU486 in spontaneously hypertensive and Sprague Dawley rats
The effect of a low dose of the glucocorticoid receptor antagonist, RU486, was tested in spontaneously hypertensive (SHR) and in Sprague Dawley (SD) rats. In SD rats, RU486 (50 gmg/day, 18 days) significantly ...
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Article
Potential for biodegradation of hydrocarbons in soil from the Ross Dependency, Antarctica
Oil spills occur in the Antarctic when fuel oils such as JP8 jet fuel are moved or stored. Hydrocarbons, both n-alkanes and aromatic compounds, have been detected in oil-contaminated soils of the Ross Dependency...
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Article
Characterization of Small Intestinal Pressure Waves in Ambulant Subjects Recorded with a Novel Portable Manometric System
The organization of lumen-occlusive pressurewaves is believed to be an important determinant ofluminal flow. At present, little is known about theorganization of small intestinal pressure waves inhumans. The a...
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Article
A novel technique for nasoduodenal feeding tube placement in critically ill patients