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Collagenase production in the exudate of a novel adjuvant-induced air pouch inflammation model in rats
To elucidate the role of collagenase in tissue destruction in chronic inflammation (e.g., in rheumatoid arthritis), we established a novel air pouch model in rats. Ten ml of air was injected subcutaneously on ...
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Article
Inhibitory effects of E-5110 on interleukin-1 generation from human monocytes
Effects of E-5110, a novel non-steroidal antiinflammatory drug, on interleukin-1 (IL-1) generation from human monocytes were studiedin vitro. E-5110 reduced the amounts of extra- and intracellular IL-1 activity i...