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    Article

    Collagenase production in the exudate of a novel adjuvant-induced air pouch inflammation model in rats

    To elucidate the role of collagenase in tissue destruction in chronic inflammation (e.g., in rheumatoid arthritis), we established a novel air pouch model in rats. Ten ml of air was injected subcutaneously on ...

    R. Hashida, K. Chiba, I. Yamatsu, K. Katayama in Agents and Actions (1991)

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    Article

    Inhibitory effects of E-5110 on interleukin-1 generation from human monocytes

    Effects of E-5110, a novel non-steroidal antiinflammatory drug, on interleukin-1 (IL-1) generation from human monocytes were studiedin vitro. E-5110 reduced the amounts of extra- and intracellular IL-1 activity i...

    Dr. H. Shirota, M. Goto, R. Hashida, I. Yamatsu, K. Katayama in Agents and Actions (1989)