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    Repopulation of B-lymphocytes with restricted gene expression using haematopoietic stem cells engineered with lentiviral vectors

    B-lymphocytes play a key role in the pathogenesis of many immune-mediated diseases, such as autoimmune and atopic diseases. Therefore, targeting B-lymphocytes provides a rationale for refining strategies to tr...

    T E Taher, C Tulone, R Fatah, F D'Acquisto, D J Gould, R A Mageed in Gene Therapy (2008)