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    Chapter

    An Ancient Cellular Mechanism in the Tension Field between Energy Requirements and Destruction Avoidance

    Circadian rhythmicity is a fundamental biological phenomenon of almost ubiquitous importance. This kind of an endogenous, innate oscillation with a period length of about a day is present in the majority of or...

    Rüdiger Hardeland in The Redox State and Circadian Rhythms (2000)

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    Chapter

    Circadian Rhythms and Oxidative Stress in Non-vertebrate Organisms

    Several lines of evidence suggest that the circadian organization of living beings is important for avoiding excessive oxidative stress under physiological conditions. In the dinoflagellate Gonyaulax polyedra, ac...

    Rüdiger Hardeland, Ana Coto-Montes… in The Redox State and Circadian Rhythms (2000)

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    Article

    Melatonin and the electron transport chain

    Melatonin protects the electron transport chain (ETC) in multiple ways. It reduces levels of ·NO by downregulating inducible and inhibiting neuronal nitric oxide synthases (iNOS, nNOS), thereby preventing exce...

    Rüdiger Hardeland in Cellular and Molecular Life Sciences (2017)