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Melatonergic Sleep Promotion: Fundamental Chronobiological Issues Concerning Sleep Onset and Maintenance, Dose and Duration of Action

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  1. Article

    Open Access

    Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues

    Since fall 2019, SARS-CoV-2 spread world-wide, causing a major pandemic with estimated ~ 220 million subjects affected as of September 2021. Severe COVID-19 is associated with multiple organ failure, particula...

    Martin Begemann, Oliver Gross, Dominik Wincewicz, Rüdiger Hardeland in Molecular Medicine (2021)

  2. Article

    Open Access

    Inducing sterile pyramidal neuronal death in mice to model distinct aspects of gray matter encephalitis

    Up to one person in a population of 10,000 is diagnosed once in lifetime with an encephalitis, in 50–70% of unknown origin. Recognized causes amount to 20–50% viral infections. Approximately one third of affec...

    Justus B. H. Wilke, Martin Hindermann in Acta Neuropathologica Communications (2021)