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  1. Article

    Advancing the global public health agenda for NAFLD: a consensus statement

    Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects approximately one-quarter of the global adult population, causing a substantial burden of ill health with wide-rang...

    Jeffrey V. Lazarus, Henry E. Mark in Nature Reviews Gastroenterology & Hepatolo… (2022)

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    Article

    Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests

    Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide and is often associated with aspects of metabolic syndrome. Despite its prevalence and the importance of early diagno...

    Mojgan Masoodi, Amalia Gastaldelli in Nature Reviews Gastroenterology & Hepatolo… (2021)

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    Article

    Defining comprehensive models of care for NAFLD

    Non-alcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease globally. Despite the increased demand placed on health-care systems, little attention has been given to the design a...

    Jeffrey V. Lazarus, Quentin M. Anstee in Nature Reviews Gastroenterology & Hepatolo… (2021)

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    Article

    From NASH to HCC: current concepts and future challenges

    Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity, nonalcoholic fatty liver disease (NAFLD), is e...

    Quentin M. Anstee, Helen L. Reeves in Nature Reviews Gastroenterology & Hepatolo… (2019)

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    Article

    Risk of cardiomyopathy and cardiac arrhythmias in patients with nonalcoholic fatty liver disease

    Nonalcoholic fatty liver disease (NAFLD) is a common, progressive liver disease that affects up to one-quarter of the adult population worldwide. The clinical and economic burden of NAFLD is mainly due to live...

    Quentin M. Anstee, Alessandro Mantovani in Nature Reviews Gastroenterology & Hepatolo… (2018)

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    Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

  7. As a consequence of the pandemic spread of obesity, NAFLD is one of the most important causes of liver disease worldwide in adults and children, although some ...

  8. Zobair Younossi, Quentin M. Anstee in Nature Reviews Gastroenterology & Hepatolo… (2018)

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    Article

    PNPLA3 and obesity: a synergistic relationship in NAFLD

    NAFLD, the hepatic manifestation of the metabolic syndrome, is a multifactorial condition — environmental factors influence an inherited genetic risk. Stender et al. now describe the additive effect of obesity a...

    Jake P. Mann, Quentin M. Anstee in Nature Reviews Gastroenterology & Hepatology (2017)

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    The genetics of NAFLD

    NAFLD is a complex disease. Considerable variability exists in the severity and risk of morbidity and mortality among individuals with NAFLD, which could be influenced by genetic and environmental factors. Her...

    Quentin M. Anstee, Christopher P. Day in Nature Reviews Gastroenterology & Hepatology (2013)

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    Article

    Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

    NAFLD is becoming much more common, and will soon be the major underlying aetiology for liver transplantation. This article discusses the evidence that NAFLD is a multisystem disease and outlines the factors t...

    Quentin M. Anstee, Giovanni Targher in Nature Reviews Gastroenterology & Hepatolo… (2013)