20 Result(s)
within
Qiu-**a Yao
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessEffect of scutellarin on BV-2 microglial-mediated apoptosis in PC12 cells via JAK2/STAT3 signalling pathway
Previous studies have shown that scutellarin inhibits the excessive activation of microglia, reduces neuronal apoptosis, and exerts neuroprotective effects. However, whether scutellarin regulates activated mic...
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Open AccessPrevalence and genetic diversity of Anaplasma and Ehrlichia in ticks and domesticated animals in Suizhou County, Hubei Province, China
Anaplasma and Ehrlichia are tick-borne bacterial pathogens that cause anaplasmoses and ehrlichioses in humans and animals. In this study, we examined the prevalence of Anaplasma and Ehrlichia species in ticks and...
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Open AccessElectron scale coherent structure as micro accelerator in the Earth’s magnetosheath
Turbulent energy dissipation is a fundamental process in plasma physics that has not been settled. It is generally believed that the turbulent energy is dissipated at electron scales leading to electron energi...
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Open AccessThe claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology
Ample evidence has suggested the stress etiology of depression, but the underlying mechanism is not fully understood yet. Here, we report that chronic social defeat stress (CSDS) attenuates the excitatory outp...
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Open AccessLight oxygen isotopes in mantle-derived magmas reflect assimilation of sub-continental lithospheric mantle material
Oxygen isotope ratios in mantle-derived magmas that differ from typical mantle values are generally attributed to crustal contamination, deeply subducted crustal material in the mantle source or primordial het...
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Article
Open AccessLPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis
Dynamic assembly and disassembly of primary cilia controls embryonic development and tissue homeostasis. Dysregulation of ciliogenesis causes human developmental diseases termed ciliopathies. Cell-intrinsic re...
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Open AccessSelf-consistent kinetic model of nested electron- and ion-scale magnetic cavities in space plasmas
NASA’s Magnetospheric Multi-Scale (MMS) mission is designed to explore the proton- and electron-gyroscale kinetics of plasma turbulence where the bulk of particle acceleration and heating takes place. Understa...
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Open AccessPlasmapause surface wave oscillates the magnetosphere and diffuse aurora
Energy circulation in geospace lies at the heart of space weather research. In the inner magnetosphere, the steep plasmapause boundary separates the cold dense plasmasphere, which corotates with the planet, fr...
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Open AccessIn-orbit operation of an atomic clock based on laser-cooled 87Rb atoms
Atomic clocks based on laser-cooled atoms are widely used as primary frequency standards. Deploying such cold atom clocks (CACs) in space is foreseen to have many applications. Here we present tests of a CAC o...
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Article
Open AccessImmunization with alkyl hydroperoxide reductase subunit C reduces Fusobacterium nucleatum load in the intestinal tract
Fusobacterium nucleatum (Fn) is an important tumour-associated bacterium in colorectal cancer (CRC). The antioxidant protein alkyl hydroperoxide reductase subunit C (AhpC) can induce stro...
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Open AccessSub-nanometre control of the coherent interaction between a single molecule and a plasmonic nanocavity
The coherent interaction between quantum emitters and photonic modes in cavities underlies many of the current strategies aiming at generating and controlling photonic quantum states. A plasmonic nanocavity pr...
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Article
Open AccessMultiple Mechanisms are Involved in Salt-Sensitive Hypertension-Induced Renal Injury and Interstitial Fibrosis
Salt-sensitive hypertension (SSHT) leads to kidney interstitial fibrosis. However, the potential mechanisms leading to renal fibrosis have not been well investigated. In present study, Dahl salt-sensitive (DS)...
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Article
Open AccessFibrosis quantification in Hypertensive Heart Disease with LVH and Non-LVH: Findings from T1 map** and Contrast-free Cardiac Diffusion-weighted imaging
This study assessed the extent of fibrosis and the relationship between the ADC value and systolic strain in hypertensive patients with left ventricular hypertrophy (HTN LVH) and hypertensive patients without ...
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Open AccessDifferences in the Clinical Characteristics of Early- and Late-Onset Necrotizing Enterocolitis in Full-Term Infants: A Retrospective Case-Control Study
Information regarding the influence of age at onset on prognosis in full-term infants with necrotizing enterocolitis (NEC) is limited, and identifying differences between the clinical characteristics of early-...
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Open AccessEvaluation of antibody level against Fusobacterium nucleatum in the serological diagnosis of colorectal cancer
Fusobacterium nucleatum (F. nucleatum, Fn) is associated with the colorectal cancer (CRC). Fn-infection could induce significant levels of serum Fn-specific antibodies in human and mice. The objective of this stu...
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Open AccessWnt4 is a novel biomarker for the early detection of kidney tubular injury after ischemia/reperfusion injury
Earlier intervention after acute kidney injury would promote better outcomes. Our previous study found that Wnt proteins are promptly upregulated after ischemic kidney injury. Thus, we assessed whether Wnt4 co...
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Article
Visualizing coherent intermolecular dipole–dipole coupling in real space
Luminescence induced by highly localized excitations that are produced by electrons tunnelling from the tip of a scanning tunnelling microscope is used to map the spatial distribution of the excitonic coupling...
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Article
Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
Nature 527, 95–99 (2015); doi:10.1038/nature15526 In this Letter, author ‘Martin Alda’ was incorrectly listed as ‘Martin Alba’ owing to a production error. In addition, ‘Ketil J. Ødegaard’ should have been lis...
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Article
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
A neuronal model of bipolar disorder based on induced pluripotent stem cell (iPSC) technology finds hyperactive action-potential firing and differential responsiveness to lithium in iPSC-derived neurons from p...
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Article
Open AccessIn vivo Optical Coherence Tomography of Light-Driven Melanosome Translocation in Retinal Pigment Epithelium
Optical coherence tomography (OCT) may revolutionize fundamental investigation and clinical management of age-related macular degeneration and other eye diseases. However, quantitative OCT interpretation is ha...
