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Open AccessAlantolactone enhances the sensitivity of melanoma to MAPK pathway inhibitors by targeting inhibition of STAT3 activation and down-regulating stem cell markers
Mitogen-activated protein kinase inhibitors (MAPKi) were the first line drugs for advanced melanoma patients with BRAF mutation. Targeted therapies have significant therapeutic effects; however, drug resistanc...
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Article
Open AccessOne-pot synthesis of stable antioxidant metal-ornamented polyphenol supramolecular assemblies for material engineering
Natural polyphenols (NPPs) are of widespread interest in material engineering; however, only a small fraction of NPPs have been utilized in biomedical applications because of their poor solubility and instabil...
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Article
Open AccessAssociation of vitamin D receptor gene polymorphisms with gestational diabetes mellitus-a case control study in Wuhan, China
Gestational diabetes mellitus (GDM) increased risk of perinatal complications for both the women and the fetuses. The association between the vitamin D receptor (VDR) gene polymorphism and GDM has not been tho...
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Article
Open AccessTime trends and risk factor associated with premature birth and infants deaths due to prematurity in Hubei Province, China from 2001 to 2012
The nutrition and epidemiologic transition has been associated with an increasing incidence of preterm birth in develo** countries, but data from large observational studies in China have been limited. Our s...
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Article
Open AccessTrajectories of length, weight, and bone mineral density among preterm infants during the first 12 months of corrected age in China
Limited evidence has been provided on the trajectories of length, weight, and bone mineral density (BMD) among preterm infants in early life in Asian countries.
