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163 Result(s)
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Article
Open AccessAn NLR paralog Pit2 generated from tandem duplication of Pit1 fine-tunes Pit1 localization and function
NLR family proteins act as intracellular receptors. Gene duplication amplifies the number of NLR genes, and subsequent mutations occasionally provide modifications to the second gene that benefits immunity. Ho...
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Open AccessAssociation between obesity and the prevalence of dyslipidemia in middle-aged and older people: an observational study
This study aimed to explore the link between various forms of obesity, including body mass index (BMI) and waist circumference (WC), and the risk of dyslipidemia among Chinese residents. We selected the study ...
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Open AccessAssociation of the CUN-BAE body adiposity estimator and other obesity indicators with cardiometabolic multimorbidity: a cross-sectional study
Cardiometabolic multimorbidity (CM), defined as the coexistence of two or three cardiometabolic disorders, is one of the most common and deleterious multimorbidities. This study aimed to investigate the associ...
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Open AccessNew Late Pleistocene age for the Homo sapiens skeleton from Liujiang southern China
The emergence of Homo sapiens in Eastern Asia is a topic of significant research interest. However, well-preserved human fossils in secure, dateable contexts in this region are extremely rare, and often the subje...
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Open AccessBoosting thermoelectric performance of single-walled carbon nanotubes-based films through rational triple treatments
Single-walled carbon nanotubes (SWCNTs)-based thermoelectric materials, valued for their flexibility, lightweight, and cost-effectiveness, show promise for wearable thermoelectric devices. However, their therm...
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Open AccessA patient-specific lung cancer assembloid model with heterogeneous tumor microenvironments
Cancer models play critical roles in basic cancer research and precision medicine. However, current in vitro cancer models are limited by their inability to mimic the three-dimensional architecture and heterog...
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Open AccessImmune protection of three serine protease inhibitors vaccine in mice against Rhipicephalus sanguineus
Bioactive molecules in tick saliva are considered to be key to successful feeding and further the transmission of tick-borne pathogens. Problems such as pathogen transmission and animal weight loss result in t...
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Open AccessAberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma
In multiple myeloma, abnormal plasma cells establish oncogenic niches within the bone marrow by engaging the NF-κB pathway to nurture their survival while they accumulate pro-proliferative mutations. Under the...
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Open AccessMADS1-regulated lemma and awn development benefits barley yield
Floral organ shape and size in cereal crops can affect grain size and yield, so genes that regulate their development are promising breeding targets. The lemma, which protects inner floral organs, can physical...
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Open AccessThermoelectric coupling effect in BNT-BZT-xGaN pyroelectric ceramics for low-grade temperature-driven energy harvesting
Pyroelectric energy harvesting has received increasing attention due to its ability to convert low-grade waste heat into electricity. However, the low output energy density driven by low-grade temperature limi...
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Open AccessTracking lake drainage events and drained lake basin vegetation dynamics across the Arctic
Widespread lake drainage can lead to large-scale drying in Arctic lake-rich areas, affecting hydrology, ecosystems and permafrost carbon dynamics. To date, the spatio-temporal distribution, driving factors, an...
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Open AccessAssessment of aortic to peripheral vascular stiffness and gradient by segmented upper limb PWV in healthy and hypertensive individuals
Theoretically pulse wave velocity (PWV) is obtained by calculating the distance between two waveform probes divided by the time difference, and PWV ratio is used to assess the arterial stiffness gradient (SG) ...
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Open AccessAmbient data-driven SSO online monitoring of type-3 wind turbine generator integrated power systems based on MMPF-KF method
Series compensation grids connected with type-3 wind turbine generator (WTG)-based wind farms have suffered numerous subsynchronous oscillation (SSO) events worldwide. For early alerting of SSO and effective d...
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Open AccessAnomalous spin current anisotropy in a noncollinear antiferromagnet
Cubic materials host high crystal symmetry and hence are not expected to support anisotropy in transport phenomena. In contrast to this common expectation, here we report an anomalous anisotropy of spin curren...
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Open AccessComparison of infection and human immune responses of two SARS-CoV-2 strains in a humanized hACE2 NIKO mouse model
The COVID-19 pandemic has sickened millions, cost lives and has devastated the global economy. Various animal models for experimental infection with SARS-CoV-2 have played a key role in many aspects of COVID-1...
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Open AccessPolarization conversion in bottom-up grown quasi-1D fibrous red phosphorus flakes
Fibrous red phosphorus (RP) has triggered growing attention as an emerging quasi-one-dimensional (quasi-1D) van der Waals crystal recently. Unfortunately, it is difficult to achieve substrate growth of high-qu...
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Open AccessAssociation between preoperative C-reactive protein to albumin ratio and late arteriovenous fistula dysfunction in hemodialysis patients: a cohort study
Arteriovenous fistula (AVF) dysfunction is a critical complication in hemodialysis (HD) patients, with inflammation potentially contributing to its development. This retrospective cohort study aimed to investi...
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Open AccessA platform trial of neoadjuvant and adjuvant antitumor vaccination alone or in combination with PD-1 antagonist and CD137 agonist antibodies in patients with resectable pancreatic adenocarcinoma
A neoadjuvant immunotherapy platform clinical trial allows for rapid evaluation of treatment-related changes in tumors and identifying targets to optimize treatment responses. We enrolled patients with resecta...
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Open AccessA new method of alternating shooting of two different seismic sources for deep geophysical surveys
In the latest geophysical survey crossing the Ninety East Ridge of the Indian Ocean, a new method was employed to perform proportional double seismic source excitation and synchronously receive signals from th...
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Open AccessTunable CO2 electroreduction to ethanol and ethylene with controllable interfacial wettability
The mechanism of how interfacial wettability impacts the CO2 electroreduction pathways to ethylene and ethanol remains unclear. This paper describes the design and realization of controllable equilibrium of kinet...