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  1. Article

    Open Access

    Penpulimab, an anti-PD-1 antibody, for heavily pretreated metastatic nasopharyngeal carcinoma: a single-arm phase II study

    Penpulimab is an anti-programmed cell death-1 (PD-1) IgG1 antibody with no Fc gamma receptor (FcγR) binding activity, and thus theoretically reduced immune-related adverse events (irAEs) while maintaining effi...

    **aozhong Chen, Wei Wang, Qingfeng Zou in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    Effects of metformin on the glucose regulation, lipid levels and gut microbiota in high-fat diet with streptozotocin induced type 2 diabetes mellitus rats

    Metformin, an anti-diabetic drug, regulates blood glucose by affecting gut microbiotas. However, the potential mechanism underlying this effect remains unclear. This study aimed to evaluate the effect of metfo...

    Xuan Zhou, Jian Zhou, Qingfeng Ban, Mei Zhang, Bo Ban in Endocrine (2024)

  3. Article

    Open Access

    Comparison of the clinical characteristics in parents and their children in a series of family clustered Mycoplasma pneumoniae infections

    Mycoplasma pneumoniae infections have increased in China recently, causing some evidence of familial clustering. The purpose of this study was to compare the clinical features of parents and children in cases of...

    Xu Liu, Qingfeng Zhang, Hao Chen, Yueying Hao, **gyi Zhang in BMC Pulmonary Medicine (2024)

  4. Article

    Open Access

    Clinical courses and outcomes of COVID-19 associated pulmonary aspergillosis in 168 patients with the SARS-CoV-2 omicron variant

    We aimed to analyze the clinical features of COVID-19-associated pulmonary aspergillosis (CAPA) during the SARS-CoV-2 Omicron variant pandemic and to reveal the risk factors for CAPA and death.

    Yixuan Wang, Yan Yao, Qingfeng Zhang, Hao Chen, Yang He, Ke Hu in BMC Infectious Diseases (2024)

  5. Article

    Open Access

    Two novel mutations within FREM1 gene in patients with bifid nose

    Bifid nose is a rare congenital deformity and the etiology is unknown. The purpose of this study was to report genetic variation in family of patients with bifid nose.

    **aoxue Chen, Baofu Yu, Zi Wang, Qingfeng Li, Chuanchang Dai, Jiao Wei in BMC Pediatrics (2023)

  6. No Access

    Article

    Effect of obstructive sleep apnea on semen quality

    Obstructive sleep apnea (OSA) has several notable complications such as hypertension and diabetes. Studies have also shown that OSA is associated with erectile dysfunction and reduced androgen levels. However,...

    Zehao Wang, Qingfeng Zhang, **li Ding, Sisi Yan, Wenyi ** in Sleep and Breathing (2023)

  7. Article

    Open Access

    Ae index is an independent predictor of kidney stone recurrence in overweight and obese patients

    Finding some convenient and economical indicators to initially screen overweight and obese patients at high risk of kidney stone recurrence can help them prevent stone recurrence with lower medical cost. The p...

    Kaiguo **a, Yuexian Xu, Qiao Qi, Jiashan Pan, Rui Yao, Qingfeng Huang in BMC Urology (2023)

  8. Article

    Open Access

    Correction: The association between air pollution and the daily hospital visits for atrial fibrillation recorded by ECG: a case-crossover study

    Jiming Han, Rui Zhang, **gyi Guo, Qingfeng Zheng in European Journal of Medical Research (2023)

  9. No Access

    Article

    NREM sleep loss increases neurofilament light chain levels in APP/PS1 and C57BL/6 J mice

    Sleep disturbances exacerbate the progression of Alzheimer’s disease (AD), but disturbances of non-rapid eye movement (NREM) sleep and rapid eye movement (REM) sleep may have different effects. Neurofilament l...

    Shunjie Liu, Zhiying Zhang, Shuangming Shi, Yangyang Meng in Sleep and Breathing (2023)

  10. Article

    Open Access

    The association between air pollution and the daily hospital visits for atrial fibrillation recorded by ECG: a case-crossover study

    The relationship between air pollution and atrial fibrillation (AF) recorded by electrocardiograph (ECG) has not yet been illustrated which worsens AF precaution and treatment. This research evaluated the asso...

    Jiming Han, Rui Zhang, **gyi Guo, Qingfeng Zheng in European Journal of Medical Research (2023)

  11. Article

    Open Access

    Diagnostic value of a nanopore sequencing assay of bronchoalveolar lavage fluid in pulmonary tuberculosis

    To determine the diagnostic accuracy of a nanopore sequencing assay of PCR products from a M. tuberculosis complex-specific region for testing of bronchoalveolar lavage fluid (BALF) samples or sputum samples f...

    Zhifeng Liu, Yang Yang, Qingfeng Wang, Lei Wang, Wenjuan Nie in BMC Pulmonary Medicine (2023)

  12. Article

    Open Access

    Bile acid predicts congenital portosystemic venous shunt in patients with pulmonary arterial hypertension

    The etiology of pulmonary arterial hypertension (PAH) is complex, especially the investigation of rare pathogeny is difficult. Congenital portosystemic venous shunt (CPSS) is a rare congenital anomaly in which...

    Yunyan Li, **aoxian Deng, Hongmei Zhou, Xuan Zheng in European Journal of Medical Research (2023)

  13. Article

    Open Access

    Association of circulating tumor cell-white blood cell clusters with survival outcomes in patients with colorectal cancer after curative intent surgery

    The analysis of circulating tumor cell-associated white blood cell (CTC-WBC) clusters represented the progress in the liquid biopsy of malignant tumors, however, related research in patients with colorectal ca...

    Yifan Xu, Qianlong Zhang, Zhou Xu, Qingfeng **e, Wenfu Ding in BMC Gastroenterology (2022)

  14. Article

    Open Access

    Surgical Strategies for Eyelid Defect Reconstruction: A Review on Principles and Techniques

    Reconstruction of eyelid defects, especially the posterior lamella, remains challenging because of its anatomical complexity, functional considerations, and aesthetic concerns. The goals of eyelid reconstructi...

    Yuxin Yan, Rao Fu, Qiumei Ji, Chuanqi Liu, **g Yang, **ya Yin in Ophthalmology and Therapy (2022)

  15. Article

    Open Access

    Distribution and drug sensitivity of pathogenic bacteria in diabetic foot ulcer patients with necrotizing fasciitis at a diabetic foot center in China

    Diabetic foot ulcer is one of the major complications for patients with diabetes, and has become an important cause of non-traumatic amputation. Necrotizing fasciitis is a life-threatening soft-tissue infectio...

    Xuemei Li, Zhipeng Du, Ziwei Tang, Qin Wen, Qingfeng Cheng in BMC Infectious Diseases (2022)

  16. Article

    Open Access

    MicroRNA-455-3p regulates proliferation and osteoclast differentiation of RAW264.7 cells by targeting PTEN

    Macrophages are one of the important cells in immune system. In this article, we aim to explore the regulatory role of miR-455-3p on proliferation and osteoblast differentiation of RAW264.7 cells.

    **aolu Zhang, Liangming Wang, Nianlai Huang, Yiqiang Zheng in BMC Musculoskeletal Disorders (2022)

  17. No Access

    Article

    Adjunctive interleukin-2 for the treatment of drug-susceptible tuberculosis: a randomized control trial in China

    Evaluation of the efficacy and safety of IL-2 in the treatment of drug-susceptible tuberculosis.

    Wenjuan Nie, Jun Wang, Jianfeng Zeng, Qingfeng Wang, Yadong Du, Qi Tan in Infection (2022)

  18. Article

    Open Access

    The impact of cardiomotor rehabilitation on endothelial function in elderly patients with chronic heart failure

    To explore the effects of cardiac exercise rehabilitation on peripheral blood endothelial progenitor cells (EPC) in elderly patients with chronic heart failure.

    Juming Chen, Shenhong Gu, Yanling Song, **nbo Ji in BMC Cardiovascular Disorders (2021)

  19. No Access

    Article

    Efficacy and Safety of the Biosimilar IBI301 Plus Standard CHOP (I-CHOP) in Comparison With Rituximab Plus CHOP (R-CHOP) in Patients with Previously Untreated Diffuse Large B-Cell Lymphoma (DLBCL): A Randomized, Double-Blind, Parallel-Group, Phase 3 Trial

    Patients with diffuse large B-cell lymphoma (DLBCL) have limited access to rituximab. IBI301 is a recombinant chimeric murine/human anti-CD20 monoclonal antibody and is a candidate biosimilar to rituximab. Th...

    Yuqin Song, Hui Zhou, Huilai Zhang, Wei Liu, Yuerong Shuang in Advances in Therapy (2021)

  20. Article

    Residents’ Willingness to Maintain Contracts with Family Doctors: a Cross-sectional Study in China

    Most previous studies of the family doctor contract services (FDCS) evaluated its quality by using residents’ signing rates, awareness, and satisfaction. We hypothesize that renewal willingness could be anothe...

    Chao Wang Ph.D, Shijiao Yan Ph.D, Heng Jiang Ph.D in Journal of General Internal Medicine (2021)

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