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Article
FAT10 induces immune suppression by upregulating PD-L1 expression in hepatocellular carcinoma
The upregulation of programmed death ligand 1 (PD-L1) plays a crucial role in facilitating cancer cells to evade immune surveillance through immunosuppression. However, the precise regulatory mechanisms of PD-...
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Article
Collaborative Localization Strategy Based on Node Selection and Power Allocation in Resource-Constrained Environments
Accurate positioning in the constrained environment of Global Navigation satellite Systems (GNSS) is a challenging problem, especially in resource-constrained urban canyon environments. In order to incentivize...
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Article
Open AccessCircNUP54 promotes hepatocellular carcinoma progression via facilitating HuR cytoplasmic export and stabilizing BIRC3 mRNA
Circular RNAs (circRNAs) have been implicated in tumorigenesis and progression of various cancers. However, the underlying mechanisms of circRNAs in hepatocellular carcinoma (HCC) have not been fully elucidate...
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Article
A novel risk score system based on immune subtypes for identifying optimal mRNA vaccination population in hepatocellular carcinoma
Although mRNA vaccines have shown certain clinical benefits in multiple malignancies, their therapeutic efficacies against hepatocellular carcinoma (HCC) remains uncertain. This study focused on establishing a...
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Article
Open AccessIdentification of FOXP1 as a favorable prognostic biomarker and tumor suppressor in intrahepatic cholangiocarcinoma
Forkhead-box protein P1 (FOXP1) has been proposed to have both oncogenic and tumor-suppressive properties, depending on tumor heterogeneity. However, the role of FOXP1 in intrahepatic cholangiocarcinoma (ICC) ...
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Article
Cooperative Task Scheduling and Planning Considering Resource Conflicts and Precedence Constraints
The robot-task-sequencing planning problem is investigated in this paper, where multi-robot tasks with resource conflicts and precedence constraints are involved making the problem challenging and complex. An ...
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Article
Open AccessPrognostic stratification based on HIF-1α signaling for evaluating hypoxia status and immune landscape in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) has a desmoplastic and hypoxic tumor microenvironment (TME), resulting in poor prognosis and treatment resistance. This study aimed to construct a novel prognostic classifier to ...
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Article
Open AccessMultiple forms of vitamin B6 regulate salt tolerance by balancing ROS and abscisic acid levels in maize root
Salt stress causes osmotic stress, ion toxicity and oxidative stress, inducing the accumulation of abscisic acid (ABA) and excessive reactive oxygen species (ROS) production, which further damage cell structur...
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Article
Expression of Tobacco Lipid Transfer Protein NtLTP4 Enhances Tolerance to Abiotic and Biotic Stresses in Transgenic Potato Lines
Potato (Solanum tuberosum L.) is the world’s most important non-grain food crops, so it is important to improve the potato yield and quality. Lipid transfer proteins (LTPs) play critical roles in various environm...
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Article
Open AccessImpacts of farmer cooperative membership on household income and inequality: Evidence from a household survey in China
While joining farmer cooperatives has been identified as a way for farmers, especially small farmers, to overcome their limitations in the marketplace and increase their income, this paper presents an analytic...
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Article
Open AccessCircLIFR suppresses hepatocellular carcinoma progression by sponging miR-624-5p and inactivating the GSK-3β/β-catenin signaling pathway
Circular RNAs have been reported to play essential roles in the tumorigenesis and progression of various cancers. However, the biological processes and mechanisms involved in hepatocellular carcinoma (HCC) rem...
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Article
Radiation protection designs of the linac for the HEPS
The high-energy photon source (HEPS) is the first fourth-generation light source under construction in China. It is designed to operate at an average current of 200 mA stored beam current with a top-up model a...
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Article
Radiation shielding for the first optics enclosure at the High Energy Photon Source beamlines
The High Energy Photon Source (HEPS) is currently under construction in China and will be the brightest synchrotron radiation facility in the world. To solve the gas bremsstrahlung and synchrotron radiation ha...
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Article
Open AccessUltrahigh-activity immune inducer from Endophytic Fungi induces tobacco resistance to virus by SA pathway and RNA silencing
Plant viruses cause severe economic losses in agricultural production. An ultrahigh activity plant immune inducer (i.e., ZhiNengCong, ZNC) was extracted from endophytic fungi, and it could promote plant growth...
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Article
Research on radiation dose rate distribution in the backscattering neutron hall of CSNS
To evaluate the prompt and induced dose rate in backscattering neutron hall for radiation protection and safety management.
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Chapter and Conference Paper
Deep Learning and Binocular Stereovision to Achieve Fast Detection and Location of Target
Air targets are often fast and varied. For air targets monitoring tasks, traditional methods tend to be slow and resource-intensive. Therefore, this paper proposes a method of target detection and location usi...
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Chapter and Conference Paper
Position Tracking and Ellipse Fitting of UAV Flying by Elliptical Trajectory
The abuse of civil UAVs poses a great threat to many important facilities. Position tracking and intention discrimination of aerial targets such as civil UAVs can help operators stop the damage caused by UAVs ...
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Chapter and Conference Paper
Approximation of Local Quasi-Geoid Using Point Mass Method Based on Bjerhammar Theory
Based on the solution for the Bjerhammar Boundary Value Problem (BVP) in physical geodesy, an approximation method of local quasi-geoid using point masses was proposed in the paper, and a multi-layer point mas...
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Article
Study on the Correction Method for the Dead-Time Effects of Neutron Detectors Due to Pulsed Radiation
Gas detectors based on a 3He proportional counter play an important role in monitoring the ambient dose equivalent in nuclear reactors and particle accelerators, and the time resolution of such gas detectors is d...
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Chapter and Conference Paper
Nest Detection Using Coarse-to-Fine Searching Strategy
Nest on pylon is a great threat to the safety and function of electric power system. Thus detection of nest has been considered as a vital task when checking transmission line through intelligent surveillance ...