106 Result(s)
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Open AccessTranscriptome sequencing of garlic reveals key genes related to the heat stress response
With global warming, heat stress has become an important factor that seriously affects crop yield and quality. Therefore, understanding plant responses to heat stress is important for agricultural practice, bu...
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Open AccessA haplotype-resolved genome assembly of Malus domestica ‘Red Fuji’
The ‘Red Fuji’ apple (Malus domestica), is one of the most important and popular economic crops worldwide in the fruit industry. Using PacBio HiFi long reads and Hi-C reads, we assembled a high-quality haplotype-...
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Article
Open AccessIn-situ observation of silk nanofibril assembly via graphene plasmonic infrared sensor
Silk nanofibrils (SNFs), the fundamental building blocks of silk fibers, endow them with exceptional properties. However, the intricate mechanism governing SNF assembly, a process involving both protein confor...
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Open AccessDisruption of TIGAR-TAK1 alleviates immunopathology in a murine model of sepsis
Macrophage-orchestrated inflammation contributes to multiple diseases including sepsis. However, the underlying mechanisms remain to be defined clearly. Here, we show that macrophage TP53-induced glycolysis an...
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Open AccessPhotonic chip-based low-noise microwave oscillator
Numerous modern technologies are reliant on the low-phase noise and exquisite timing stability of microwave signals. Substantial progress has been made in the field of microwave photonics, whereby low-noise mi...
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Article
Open AccessGenetic drivers of heterogeneity in type 2 diabetes pathophysiology
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic c...
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Open AccessLow pressure reversibly driving colossal barocaloric effect in two-dimensional vdW alkylammonium halides
Plastic crystals as barocaloric materials exhibit the large entropy change rivalling freon, however, the limited pressure-sensitivity and large hysteresis of phase transition hinder the colossal barocaloric ef...
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Open AccessPro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence
Senescence of vascular smooth muscle cells (VSMCs) contributes to aging-related cardiovascular diseases by promoting arterial remodelling and stiffness. Ferroptosis is a novel type of regulated cell death asso...
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Open AccessMushroom poisoning outbreaks in Guizhou Province, China: a prediction study using SARIMA and Prophet models
Mushroom poisoning is a public health concern worldwide that not only harms the physical and mental health of those who are poisoned but also increases the medical and financial burden on families and society....
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Open AccessBacterial genome size and gene functional diversity negatively correlate with taxonomic diversity along a pH gradient
Bacterial gene repertoires reflect adaptive strategies, contribute to ecosystem functioning and are limited by genome size. However, gene functional diversity does not necessarily correlate with taxonomic dive...
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Open AccessCo-option of a non-retroviral endogenous viral element in planthoppers
Non-retroviral endogenous viral elements (nrEVEs) are widely dispersed throughout the genomes of eukaryotes. Although nrEVEs are known to be involved in host antiviral immunity, it remains an open question whe...
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Open AccessNucleophilic aromatization of monoterpenes from isoprene under nickel/iodine cascade catalysis
As a large number of organic compounds possessing two isoprene units, monoterpenes and monoterpenoids play important roles in pharmaceutical, cosmetic, agricultural, and food industries. In nature, monoterpene...
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Open AccessSingle virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy
Clinical identification and fundamental study of viruses rely on the detection of viral proteins or viral nucleic acids. Yet, amplification-based and antigen-based methods are not able to provide precise compo...
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Article
Open AccessA de novo evolved gene contributes to rice grain shape difference between indica and japonica
The role of de novo evolved genes from non-coding sequences in regulating morphological differentiation between species/subspecies remains largely unknown. Here, we show that a rice de novo gene GSE9 contributes ...
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Open AccessCharacterization of two O-methyltransferases involved in the biosynthesis of O-methylated catechins in tea plant
Tea is known for having a high catechin content, with the main component being (−)-epigallocatechin gallate (EGCG), which has significant bioactivities, including potential anti-cancer and anti-inflammatory ac...
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Open Access3D integration enables ultralow-noise isolator-free lasers in silicon photonics
Photonic integrated circuits are widely used in applications such as telecommunications and data-centre interconnects1–5. However, in optical systems such as microwave synthesizers6, optical gyroscopes7 and atomi...
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Open AccessPolar Solomon rings in ferroelectric nanocrystals
Solomon rings, upholding the symbol of wisdom with profound historical roots, were widely used as decorations in ancient architecture and clothing. However, it was only recently discovered that such topologica...
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Open AccessSignalling by senescent melanocytes hyperactivates hair growth
Niche signals maintain stem cells in a prolonged quiescence or transiently activate them for proper regeneration1. Altering balanced niche signalling can lead to regenerative disorders. Melanocytic skin nevi in h...
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Open AccessGenome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study o...
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Open AccessEffects of total daily light integral from blue and broad-band red LEDs on flowering of saffron (Crocus sativus L.)
Present indoor cultivation of saffron (Crocus sativus L.) only depends on artificial planting experience, so that flower number and stigma yield are seriously affected in case of cloudy or rainy days and temperat...
