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217 Result(s)
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Article
Hi-TOM 2.0: an improved platform for high-throughput mutation detection
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Article
hsa_circ_0002454 controls cervical cancer cell growth and metastasis by targeting SDC4 through miR-654-3p
Circular RNAs (circRNAs) are involved in tumor growth and metastasis. The aim of this study was to elucidate the possible role of has_circ_0002454 in cervical cancer (CC) and its potential molecular mechanism.
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Article
NaCl improves the vegetable quality of Mesembryanthemum crystallinum Linn. by increasing betacyanin and nutrient contents
Soil salinization is a growing environmental problem and a major factor limiting crop production. Growing salt-adapted crops may allow farmers to utilize farmland with high salt concentrations. For example, le...
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Article
Photosynthetic activity and astaxanthin production of Haematococcus pluvialis regulated by manipulated light quality
Haematococcus pluvialis produces astaxanthin in response to light quality of illumination. To better understand the responses to the combinations of monochromatic red and blue light, the growth, cell differentiat...
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Article
TROP2 promotes the proliferation of triple-negative breast cancer cells via calcium ion-dependent ER stress signaling pathway
Objective: To explore the molecular mechanisms of tumor-associated calcium signal transduction factor 2 (TROP2) affecting the occurrence and development of triple-negative breast cancer (TNBC). Methods: The TC...
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Article
Open AccessEfficacy and safety of novel multifunctional M10 CAR-T cells in HIV-1-infected patients: a phase I, multicenter, single-arm, open-label study
Chimeric antigen receptor T (CAR-T) cells have been proposed for HIV-1 treatment but have not yet demonstrated desirable therapeutic efficacy. Here, we report newly developed anti-HIV-1 CAR-T cells armed with ...
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Article
Open AccessOsLSC6 Regulates Leaf Sheath Color and Cold Tolerance in Rice Revealed by Metabolite Genome Wide Association Study
Plant metabolites including anthocyanins play an important role in the growth of plants, as well as in regulating biotic and abiotic stress responses to the environment. Here we report comprehensive profiling ...
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Article
Argon non-thermal plasma treatment promotes the development of rice (Oryza sativa L.) in saline alkali environments
Soil salinization leads to a reduction in arable land area, which seriously endangers food security. Develo** saline-alkali land has become a key measure to address the contradiction between population growt...
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Article
Isolation and Functional Analysis of Na+/H+ Antiporter Gene (LcNHX1) from Leymus chinensis
Saline-alkali stress has adverse effects on plant growth. Some plant Na+/H+ antiporters were reported to be important in salt tolerance. However, it needs to be better understood that Na+/H+ antiporters are invol...
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Article
Coordination of leaf and root economic space in alpine coniferous forests on the Tibetan Plateau
Coordination between leaf and root traits is crucial to plant performance and ecosystem functioning, but how leaves and roots coordinate in ectomycorrhizal (ECM)-dominated alpine forests remains unclear. There...
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Article
Open AccessTranscription factor encoding gene OsC1 regulates leaf sheath color through anthocyanidin metabolism in Oryza rufipogon and Oryza sativa
Carbohydrates, proteins, lipids, minerals and vitamins are nutrient substances commonly seen in rice grains, but anthocyanidin, with benefit for plant growth and animal health, exists mainly in the common wild...
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Article
Open AccessStructure-aware deep model for MHC-II peptide binding affinity prediction
The prediction of major histocompatibility complex (MHC)-peptide binding affinity is an important branch in immune bioinformatics, especially helpful in accelerating the design of disease vaccines and immunity...
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Article
Correction to: Safety assessment, whole genome sequence, and metabolome analysis of Streptococcus thermophilus CICC 20372 for bone cement fermentation
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Article
Open AccessMKK3 Cascade Regulates Seed Dormancy Through a Negative Feedback Loop Modulating ABA Signal in Rice
With the increasing frequency of climatic anomalies, high temperatures and long-term rain often occur during the rice-harvesting period, especially for early rice crops in tropical and subtropical regions. See...
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Article
Gene editing of ZmGA20ox3 improves plant architecture and drought tolerance in maize
Editing ZmGA20ox3 can achieve the effect similar to applying Cycocel, which can reduce maize plant height and enhance stress resistance.
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Article
Exogenous 6-BA enhances salt tolerance of Limonium bicolor by increasing the number of salt glands
Exogenous 6-BA can increase endogenous hormone content, improve photosynthesis, decrease Na+ by increasing leaf salt gland density and salt secretion ability, and reduce ROS content so that it can promote L. bico...
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Article
Safety assessment, whole genome sequence, and metabolome analysis of Streptococcus thermophilus CICC 20372 for bone cement fermentation
Bone is a kind of meat processing by-product with high nutritional value but low in calorie, which is a typical food in China and parts of East Asian countries. Microbial fermentation by lactic acid bacteria s...
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Open AccessGenome-wide expansion and reorganization during grass evolution: from 30 Mb chromosomes in rice and Brachypodium to 550 Mb in Avena
The BOP (Bambusoideae, Oryzoideae, and Pooideae) clade of the Poaceae has a common ancestor, with similarities to the genomes of rice, Oryza sativa (2n = 24; genome size 389 Mb) and Brachypodium, Brachypodium dis...
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Article
Combined QTL-seq and QTL map** strategies identify genes related to alkalinity tolerance in rice seedlings
Soil alkalinity can expose plants to deleterious stress that can limit plant growth and development, reducing crop productivity. While many studies have explored the damage that high salt levels can cause to r...
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Open AccessGenome-wide identification of the mitogen-activated kinase gene family from Limonium bicolor and functional characterization of LbMAPK2 under salt stress
Mitogen-activated protein kinases (MAPKs) are ubiquitous signal transduction components in eukaryotes. In plants, MAPKs play an essential role in growth and development, phytohormone regulation, and abiotic st...