Skip to main content

6 Result(s)

within Qiangfeng Cliff Zhang Remove this filter English Remove this filter Biochemistry, general Remove this filter

and

  1. No Access

    Article

    Structural insights into branch site proofreading by human spliceosome

    Selection of the pre-mRNA branch site (BS) by the U2 small nuclear ribonucleoprotein (snRNP) is crucial to prespliceosome (A complex) assembly. The RNA helicase PRP5 proofreads BS selection but the underlying ...

    **aofeng Zhang, **echao Zhan, Tong Bian… in Nature Structural & Molecular Biology (2024)

  2. No Access

    Article

    RNA structure probing uncovers RNA structure-dependent biological functions

    RNA molecules fold into complex structures that enable their diverse functions in cells. Recent revolutionary innovations in transcriptome-wide RNA structural probing of living cells have ushered in a new era ...

    **-Wen Wang, Chu-**ao Liu, Ling-Ling Chen, Qiangfeng Cliff Zhang in Nature Chemical Biology (2021)

  3. No Access

    Article

    Keth-seq for transcriptome-wide RNA structure map**

    RNA secondary structure is critical to RNA regulation and function. We report a new N3-kethoxal reagent that allows fast and reversible labeling of single-stranded guanine bases in live cells. This N3-kethoxal-ba...

    **aocheng Weng, **g Gong, Yi Chen, Tong Wu, Fang Wang… in Nature Chemical Biology (2020)

  4. No Access

    Article

    RNA structure maps across mammalian cellular compartments

    RNA structure is intimately connected to each step of gene expression. Recent advances have enabled transcriptome-wide maps of RNA secondary structure, called ‘RNA structuromes’. However, previous whole-cell a...

    Lei Sun, Furqan M. Fazal, Pan Li… in Nature Structural & Molecular Biology (2019)

  5. Article

    Erratum to: Solution NMR structures reveal unique homodimer formation by a winged helix-turn-helix motif and provide first structures for protein domain family PF10771

    Alexander Eletsky, Donald Petrey… in Journal of Structural and Functional Genom… (2012)

    Download PDF (95 KB) View Article

  6. No Access

    Article

    Solution NMR structures reveal unique homodimer formation by a winged helix-turn-helix motif and provide first structures for protein domain family PF10771

    High-quality NMR structures of the homo-dimeric proteins Bvu3908 (69-residues in monomeric unit) from Bacteroides vulgatus and Bt2368 (74-residues) from Bacteroides thetaiotaomicron reveal the presence of winged ...

    Alexander Eletsky, Donald Petrey… in Journal of Structural and Functional Genom… (2012)