45 Result(s)

Article

KSNP: a fast de Bruijn graph-based haploty** tool approaching data-in time cost

Long reads that cover more variants per read raise opportunities for accurate haplotype construction, whereas the genotype errors of single nucleotide polymorphisms pose great computational challenges for hapl...

Qian Zhou, Fahu Ji, Dongxiao Lin, **anming Liu, Zexuan Zhu… in Nature Communications (2024)

Article

Long lifetimes white afterglow in slightly crosslinked polymer systems

Intrinsic polymer room-temperature phosphorescence (IPRTP) materials have attracted considerable attention for application in flexible electronics, information encryption, lighting displays, and other fields d...

Qingao Chen, Lunjun Qu, Hui Hou, Jiayue Huang, Chen Li, Ying Zhu… in Nature Communications (2024)

Article

Author Correction: Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function

Yuman Wang, Zaiqiao Sun, Jieming **, Jianlong Tang, Boxiao He… in Nature Communications (2024)

Article

Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function

Biosynthesis drives the cell volume increase during T cell activation. However, the contribution of cell volume regulation in TCR signaling during T lymphoblast formation and its underlying mechanisms remain u...

Yuman Wang, Zaiqiao Sun, Jieming **, Jianlong Tang, Boxiao He… in Nature Communications (2023)

Article

UV-B irradiation-activated E3 ligase GmILPA1 modulates gibberellin catabolism to increase plant height in soybean

Plant height is a key agronomic trait that affects yield and is controlled by both phytohormone gibberellin (GA) and ultraviolet-B (UV-B) irradiation. However, whether and how plant height is modulated by UV-B...

Jiaqi Sun, Shiyu Huang, Qing Lu, Shuo Li, Shizhen Zhao… in Nature Communications (2023)

Article

A CCL2⁺DPP4⁺ subset of mesenchymal stem cells expedites aberrant formation of cree** fat in humans

Cree** fat is a typical feature of Crohn’s disease. It refers to the expansion of mesenteric adipose tissue around inflamed and fibrotic intestines and is associated with stricture formation and intestinal o...

Fengfei Wu, Fangting Wu, Qian Zhou, ** Liu, Jieying Fei, Da Zhang… in Nature Communications (2023)

Article

A parabrachial-hypothalamic parallel circuit governs cold defense in mice

Thermal homeostasis is vital for mammals and is controlled by brain neurocircuits. Yet, the neural pathways responsible for cold defense regulation are still unclear. Here, we found that a pathway from the lat...

Wen Z. Yang, Hengchang **e, **aosa Du, Qian Zhou, Yan **ao… in Nature Communications (2023)

Article

Serum and supplemental vitamin D levels and insulin resistance in T2DM populations: a meta-analysis and systematic review

Observational studies have shown a negative correlation between Vitamin D level and the likelihood of develo** insulin resistance (IR) and/or diabetes over time, yet evidence remains inconsistent. In this me...

**ngxing Lei, Qian Zhou, Yanmei Wang, Shunlian Fu, Zinan Li, Qiu Chen in Scientific Reports (2023)

Article

Serological response following COVID-19 vaccines in patients living with HIV: a dose–response meta-analysis

To quantify the pooled rate and risk ratio of seroconversion following the uncomplete, complete, or booster dose of COVID-19 vaccines in patients living with HIV. PubMed, Embase and Cochrane library were searc...

Qian Zhou, Furong Zeng, Yu Meng, Yihuang Liu, Hong Liu… in Scientific Reports (2023)

Article

Construction of a synthetic methodology-based library and its application in identifying a GIT/PIX protein–protein interaction inhibitor

In recent years, the flourishing of synthetic methodology studies has provided concise access to numerous molecules with new chemical space. These compounds form a large library with unique scaffolds, but thei...

**g Gu, Rui-Kun Peng, Chun-Ling Guo, Meng Zhang, Jie Yang… in Nature Communications (2022)

Article

Aqueous hybrid electrochemical capacitors with ultra-high energy density approaching for thousand-volts alternating current line filtering

Filtering capacitors with wide operating voltage range are essential for smoothing ripples in line-powered system, which are still unsatisfactory due to low energy density and limited working voltage scopes. H...

Zhou Li, **aopeng Wang, Lingyu Zhao, Fengyao Chi, Chang Gao… in Nature Communications (2022)

Article

Phenylalanine impairs insulin signaling and inhibits glucose uptake through modification of IRβ

Whether amino acids act on cellular insulin signaling remains unclear, given that increased circulating amino acid levels are associated with the onset of type 2 diabetes (T2D). Here, we report that phenylalan...

Qian Zhou, Wan-Wan Sun, Jia-Cong Chen, Hui-Lu Zhang, Jie Liu… in Nature Communications (2022)

Article

Circulating acyl and des-acyl ghrelin levels in obese adults: a systematic review and meta-analysis

Ghrelin is the only known orexigenic gut hormone, and its synthesis, secretion and degradation are affected by different metabolic statuses. This meta-analysis aimed to investigate the potential differences in...

Yanmei Wang, Qianxian Wu, Qian Zhou, Yuyu Chen, **ngxing Lei… in Scientific Reports (2022)

Article

Sonoporation generates downstream cellular impact after membrane resealing

Sonoporation via microbubble-mediated ultrasound exposure has shown potential in drug and gene delivery. However, there is a general lack of mechanistic knowledge on sonoporation-induced cellular impact after ...

**nxing Duan, Qian Zhou, Jennifer M. F. Wan, Alfred C. H. Yu in Scientific Reports (2021)

Article

PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome

The formation of zygote is the beginning of mammalian life, and dynamic epigenetic modifications are essential for mammalian normal development. H3K27 di-methylation (H3K27me2) and H3K27 tri-methylation (H3K27...

Tie-Gang Meng, Qian Zhou, Xue-Shan Ma, **ao-Yu Liu, Qing-Ren Meng… in Nature Communications (2020)

Article

Draft genomes of female and male turbot Scophthalmus maximus

Turbot (Scophthalmus maximus) is a commercially important flatfish species in aquaculture. It has a drastic sexual dimorphism, with females growing faster than males. In the present study, we sequenced and de nov...

**-wen Xu, Chang-wei Shao, Hao Xu, Qian Zhou, Feng You, Na Wang… in Scientific Data (2020)

Article

Gene expression in immortalized versus primary isolated cardiac endothelial cells

Endothelial cells take pivotal roles in the heart and the vascular system and their differentiation, subspecification and function is determined by gene expression. A stable, in vitro cardiac endothelial cell lin...

Lisa Deng, Luisa Pollmeier, Qian Zhou, Stella Bergemann… in Scientific Reports (2020)

Article

The wax gourd genomes offer insights into the genetic diversity and ancestral cucurbit karyotype

The botanical family Cucurbitaceae includes a variety of fruit crops with global or local economic importance. How their genomes evolve and the genetic basis of diversity remain largely unexplored. In this stu...

Dasen **e, Yuanchao Xu, **peng Wang, Wenrui Liu, Qian Zhou… in Nature Communications (2019)

Article

Comparative transcriptome profiling of immune response against Vibrio harveyi infection in Chinese tongue sole

Vibrio harveyi is a major bacterial pathogen that causes fatal vibriosis in Chinese tongue sole (Cynoglossus semilaevis), resulting in massive mortality in the farming industry. However, the molecular mechanisms ...

Hao Xu, **wen Xu, **hong Li, Lei Wang, Jiayu Cheng, Qian Zhou… in Scientific Data (2019)