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Article
Open AccessSignaling pathways in rheumatoid arthritis: implications for targeted therapy
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease progression leads to joint deformity and associated loss of function, which significantly impacts the quality of life for sufferer...
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Article
Open AccessSTAT3-NAV2 axis as a new therapeutic target for rheumatoid arthritis via activating SSH1L/Cofilin-1 signaling pathway
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Article
Downregulated expression of hepatoma-derived growth factor (HDGF) reduces gallbladder cancer cell proliferation and invasion
Hepatoma-derived growth factor (HDGF), a heparin-binding growth factor, has a wide range of biological functions, including mitogenic activity and vascular development. Recent studies demonstrated that HDGF al...
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Article
Predictive factors of brain metastasis in patients with breast cancer
The aim of this study is to determine the risk factors associated with metastasis to the brain of primary breast cancer patients and evaluate a predictive model. The clinicopathological characteristics of 206 ...
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Article
PI-103 sensitizes acute myeloid leukemia stem cells to daunorubicin-induced cytotoxicity
To date, acute myeloid leukemia (AML) shows very poor outcome for conventional chemotherapy. Leukemia stem cells (LSCs) are insensitive to conventional chemotherapeutic drugs and play a central role in the pat...