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  1. No Access

    Article

    miR-374a-CCND1-pPI3K/AKT-c-JUN feedback loop modulated by PDCD4 suppresses cell growth, metastasis, and sensitizes nasopharyngeal carcinoma to cisplatin

    miR-374a has been reported to function as an oncogene during tumor pathogenesis. In this study, miR-374a is observed to reduce nasopharyngeal carcinoma (NPC) cell proliferation, migration, invasion, metastasis...

    Y Zhen, W Fang, M Zhao, R Luo, Y Liu, Q Fu, Y Chen, C Cheng, Y Zhang, Z Liu in Oncogene (2017)

  2. No Access

    Article

    A short-term transition from a high-fat diet to a normal-fat diet before pregnancy exacerbates female mouse offspring obesity

    Recent findings have highlighted the detrimental influence of maternal overnutrition and obesity on fetal development and early life development. However, there are no evidence-based guidelines regarding the o...

    Q Fu, P Olson, D Rasmussen, B Keith, M Williamson… in International Journal of Obesity (2016)

  3. No Access

    Article

    PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing β-catenin expression and nuclear translocation

    Aberrant activation of the Wnt/β-catenin pathway is frequent in hepatocellular carcinoma (HCC) and contributes to HCC initiation and progression. This abnormal activation may result from somatic mutations in t...

    Y Liu, X Ye, J-B Zhang, H Ouyang, Z Shen, Y Wu, W Wang, J Wu, S Tao, X Yang… in Oncogene (2015)

  4. No Access

    Article

    Obesity enhanced respiratory health effects of ambient air pollution in Chinese children: the Seven Northeastern Cities study

    Experimental data suggest that obesity enhances the effects of ambient air pollutants on exacerbation of asthma; however, there is little supporting epidemiological evidence. The aim of present study is to eva...

    G H Dong, Z Qian, M-M Liu, D Wang, W-H Ren, Q Fu… in International Journal of Obesity (2013)

  5. No Access

    Article

    Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty

    Genome-wide association studies (GWAS) have identified some common variants associated with obesity risk in European descents. However, their influences on obesity-related indices for the Chinese children at p...

    J Wang, H Mei, W Chen, Y Jiang, W Sun, F Li, Q Fu… in International Journal of Obesity (2012)

  6. No Access

    Article

    Androgen receptor coregulators NOCR1, TIF2, and ARA70 may account for the hydroxyflutamide insensitivity of prostate cancer cells

    Prostate cancer cells can switch from an androgen-dependent state to an androgen-independent state after a continuous androgen ablation therapy. However, the molecular mechanisms underlying this switch are sti...

    Y. Wang, J.-Q. Li, C. Shao, C.-H. Shi, F. Liu… in Irish Journal of Medical Science (2011)

  7. No Access

    Article

    Combined influence of physical activity and television viewing on the risk of overweight in US youth

    The purpose of this study was to examine the combined influence of physical activity (PA) and television viewing (TV) on the risk of overweight in US youth ages 14–18 years.

    J C Eisenmann, R T Bartee, D T Smith, G J Welk, Q Fu in International Journal of Obesity (2008)