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Article
Real-Time Analytics: Benefits, Limitations, and Tradeoffs
Real-time analytics is a relatively new branch of analytics. A common definition of real-time analytics is that it consists in analyzing data as quickly as possible over the most recent data possible. This def...
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Article
An Improved Model to Describe the Creep Behavior of Soft Soil
The creep characteristics of soft soil from the Luogang District of Guangzhou (China) were analyzed using a laboratory-based direct shear creep apparatus. Normal stress was applied to the samples, and the corr...
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Article
Open AccessEffect of Bacillus subtilis on corrosion behavior of 10MnNiCrCu steel in marine environment
Bacillus widely exists in wet natural environment such as soil, water and air, and is often studied as one of representative microorganisms for microbiologically influenced corrosion(MIC) research. In this pap...
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Article
Does U.S. Household Financial Access Mediate the Relationship Between a Large Income Drop and Credit Record?
Household financial access, in the form of savings, investments, credit, and others, can provide the means to smooth consumption and make on-time payments when large income drops occur. This study examined the...
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Article
A cardioid oscillator with asymmetric time ratio for establishing CPG models
Nonlinear oscillators are usually utilized by bionic scientists for establishing central pattern generator models for imitating rhythmic motions by bionic scientists. In the natural word, many rhythmic motions...
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Article
Analysis of the Spatial Variation and Identification of Factors Affecting the Water Resources Carrying Capacity Based on the Cloud Model
To objectively analyze the effect of the water resources carrying capacity (WRCC) on sustainable regional development, a case study of Heilongjiang Province, China, is conducted. With a focus on the coordinate...
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Article
Open AccessSimulated differences in 21st century aridity due to different scenarios of greenhouse gases and aerosols
Aridity, defined as the ratio of precipitation (P) to potential evapotranspiration (PET) over land, is critical to natural ecosystems and agricultural production. Global climate models project global decreases...
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Article
Development of solar flares and features of the fine structure of solar radio emission
The reason for the occurrence of different elements of the fine structure of solar radio bursts in the decimeter and centimeter wavelength ranges has been determined based on all available data from terrestria...
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Article
miR-374a-CCND1-pPI3K/AKT-c-JUN feedback loop modulated by PDCD4 suppresses cell growth, metastasis, and sensitizes nasopharyngeal carcinoma to cisplatin
miR-374a has been reported to function as an oncogene during tumor pathogenesis. In this study, miR-374a is observed to reduce nasopharyngeal carcinoma (NPC) cell proliferation, migration, invasion, metastasis...
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Article
A short-term transition from a high-fat diet to a normal-fat diet before pregnancy exacerbates female mouse offspring obesity
Recent findings have highlighted the detrimental influence of maternal overnutrition and obesity on fetal development and early life development. However, there are no evidence-based guidelines regarding the o...
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Article
A survey of outcomes and management of patients post fragility fractures in China
We found that the fragility hip and vertebral fractures caused excess mortality rates in this Chinese female population, which was unexpectedly lower than those in western countries and other Asian countries. ...
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Article
The assay and clinical significance of serum thymidine kinase 1 in patients with colorectal carcinoma
Thymidine kinase 1 was regarded as a good serological marker for cell proliferation. In recent years, the role of thymidine kinase 1 in occurrence, development, and prognosis of tumors gradually attracted peop...
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Article
PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing β-catenin expression and nuclear translocation
Aberrant activation of the Wnt/β-catenin pathway is frequent in hepatocellular carcinoma (HCC) and contributes to HCC initiation and progression. This abnormal activation may result from somatic mutations in t...
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Article
Open AccessProgrammed Hydrolysis in Designing Paclitaxel Prodrug for Nanocarrier Assembly
Nanocarriers delivering prodrugs are a way of improving in vivo effectiveness and efficiency. For therapeutic efficacy, the prodrug must hydrolyze to its parent drug after administration. Based on the fact that t...
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Article
Comparisons of sarcopenia prevalence based on different diagnostic criteria in Chinese older adults
The study aimed to describe the prevalence of sarcopenia and discussed the applicability of different diagnostic criteria in Chinese older adults. 286 Chinese adults (136 men and 150 women) aged 60–88 were rec...
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Article
Open AccessDeficiency of osteoblastic Arl6ip5 impaired osteoblast differentiation and enhanced osteoclastogenesis via disturbance of ER calcium homeostasis and induction of ER stress-mediated apoptosis
ADP-ribosylation-like factor 6 interacting protein 5 (Arl6ip5), which belongs to the prenylated rab-acceptor-family, has an important role in exocytic protein trafficking, glutathione metabolism and involves i...
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Article
Open AccessDownregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma
It is largely recognized that fibroblast activation protein (FAP) is expressed in cancer-associated fibroblasts (CAFs) of many human carcinomas. Furthermore, FAP was recently also reported to be expressed in c...
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Article
Estrogen increases the transcription of human α2-Heremans-Schmid-glycoprotein by an interplay of estrogen receptor α and activator protein-1
The expression of α2-Heremans-Schmid-glycoprotein (AHSG) was estrogen responsive in oophorectomized (OVX) osteopenic rats and HepG2 cells. Estrogen receptor α (ERα) interacted with the c-Jun/c-Fos heterodimer and...
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Chapter
Implicit Learning and Recursion
Implicit learning research has focused on learning simple structures, such as chunks, even though such structures do not capture the richness of real-world human accomplishments. In particular, music and langu...
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Article
Open AccessIntracellular patterns of sialophorin expression define a new molecular classification of breast cancer and represent new targets for therapy
Sialophorin is a transmembrane sialoglycoprotein. Normally, the molecule is only produced by white blood cells where it regulates functions such as intercellular adhesion, intracellular signalling, apoptosis, ...