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    Open Access

    Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer

    Treatment with regorafenib, a multiple-kinase inhibitor, to manage metastatic colorectal cancers (mCRCs) shows a modest improvement in overall survival but is associated with severe toxicities. Thus, to reduce...

    Prachi Bajpai, Sumit Agarwal, Farrukh Afaq… in Journal of Experimental & Clinical Cancer … (2024)

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