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Article
Thermal studies on oligosilylbiguanides: A mechanistic approach
Thermal decomposition of oligo-1,4-bis(silyl)-5-propyl/phenylbiguanides, 1–4 under controlled conditions (130–140 °C/N2) proceeds predominantly via the formation of organic amines, cyclic silazanes and cyclic sil...
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Article
Open AccessHigh-resolution deconstruction of evolution induced by chemotherapy treatments in breast cancer xenografts
The processes by which tumors evolve are essential to the efficacy of treatment, but quantitative understanding of intratumoral dynamics has been limited. Although intratumoral heterogeneity is common, quantif...
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Chapter and Conference Paper
A Proactive Approach to Combating the Opioid Crisis Using Machine Learning Techniques
The use of big data analytics tools and Machine Learning techniques in identifying and predicting opioid use disorder is a relatively new and emerging area. Previous studies analyzing trends in the opioid cris...
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Article
Open AccessHigh-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology with Cellos
Three-dimensional (3D) organoid cultures are flexible systems to interrogate cellular growth, morphology, multicellular spatial architecture, and cellular interactions in response to treatment. However, comput...
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Article
Increasing Access to Care: Impact of a Student-Led Fee Assistance Application Clinic
Patients seen at student-run free clinics are often limited in the extent of services they can receive through these outpatient clinics. We initiated a student-led program assisting patients to apply for the l...
