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Article

Lamotrigine Is Neuroprotective in the Energy Deficiency Model of MPTP Intoxicated Mice

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) inhibits the mitochondrial complex I of the respiratory chain. This results in ATP and ion homeostasis disturbances, which lead to selective death of the...

Emmanuelle Lagrue, Sylvie Chalon, Sylvie Bodard, Elie Saliba… in Pediatric Research (2007)