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Article
Open AccessLentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis
Increased cellular iron levels are associated with high mortality in HIV-1 infection. Moreover iron is an important cofactor for viral replication, raising the question whether highly divergent lentiviruses ac...
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Article
Open AccessNef variants from non-pathogenic lentiviral strains inhibit iron uptake through an AP2-dependent inhibition of transferrin endocytosis
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Article
Open AccessHIV-1 assembly in macrophages
The molecular mechanisms involved in the assembly of newly synthesized Human Immunodeficiency Virus (HIV) particles are poorly understood. Most of the work on HIV-1 assembly has been performed in T cells in wh...
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Article
Open AccessA multi-Fc-species system for recombinant antibody production
Genomic, transcriptomic and proteomic projects often suffer from a lack of functional validation creating a strong demand for specific and versatile antibodies. Antibody phage display represents an attractive ...