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  1. Article

    Open Access

    Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis

    Increased cellular iron levels are associated with high mortality in HIV-1 infection. Moreover iron is an important cofactor for viral replication, raising the question whether highly divergent lentiviruses ac...

    Herwig Koppensteiner, Kristin Höhne, Marcos Vinicius Gondim… in Retrovirology (2014)

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  2. Article

    Open Access

    Nef variants from non-pathogenic lentiviral strains inhibit iron uptake through an AP2-dependent inhibition of transferrin endocytosis

    Herwig Koppensteiner, Kristin Höhne, Marcos Vinicius Gondim… in Retrovirology (2013)

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  3. Article

    Open Access

    HIV-1 assembly in macrophages

    The molecular mechanisms involved in the assembly of newly synthesized Human Immunodeficiency Virus (HIV) particles are poorly understood. Most of the work on HIV-1 assembly has been performed in T cells in wh...

    Philippe Benaroch, Elisabeth Billard, Raphaël Gaudin, Michael Schindler… in Retrovirology (2010)

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  4. No Access

    Article

    Rab27a and Rab27b control different steps of the exosome secretion pathway

    Exosome biogenesis is poorly understood. The small GTPases Rab27a and Rab27b and their effectors, Slp4 and Slac2b, control exosome secretion at different steps by regulating the peripheral localization, retent...

    Matias Ostrowski, Nuno B. Carmo, Sophie Krumeich, Isabelle Fanget… in Nature Cell Biology (2010)