Skip to main content

10 Result(s)

within Philippe Benaroch Remove this filter English Remove this filter

and

  1. No Access

    Article

    Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells

    Macrophages have a key role in sha** the tumour microenvironment (TME), tumour immunity and response to immunotherapy, which makes them an important target for cancer treatment1,2. However, modulating macrophag...

    María Casanova-Acebes, Erica Dalla, Andrew M. Leader, Jessica LeBerichel… in Nature (2021)

  2. No Access

    Article

    Macrophages hide HIV in the urethra

    Eradicating the viral reservoir remains a formidable barrier to curing human immunodeficiency virus (HIV). The first challenge is to characterize the cells and tissues where HIV hides. In this issue of Nature Mic...

    Vasco Rodrigues, Philippe Benaroch in Nature Microbiology (2019)

  3. Article

    Open Access

    Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis

    Increased cellular iron levels are associated with high mortality in HIV-1 infection. Moreover iron is an important cofactor for viral replication, raising the question whether highly divergent lentiviruses ac...

    Herwig Koppensteiner, Kristin Höhne, Marcos Vinicius Gondim… in Retrovirology (2014)

    Download PDF (2518 KB) View Article

  4. Article

    Open Access

    Nef variants from non-pathogenic lentiviral strains inhibit iron uptake through an AP2-dependent inhibition of transferrin endocytosis

    Herwig Koppensteiner, Kristin Höhne, Marcos Vinicius Gondim… in Retrovirology (2013)

    Download PDF (237 KB) View Article

  5. Article

    Open Access

    HIV-1 assembly in macrophages

    The molecular mechanisms involved in the assembly of newly synthesized Human Immunodeficiency Virus (HIV) particles are poorly understood. Most of the work on HIV-1 assembly has been performed in T cells in wh...

    Philippe Benaroch, Elisabeth Billard, Raphaël Gaudin, Michael Schindler… in Retrovirology (2010)

    Download PDF (1675 KB) View Article

  6. No Access

    Article

    Rab27a and Rab27b control different steps of the exosome secretion pathway

    Exosome biogenesis is poorly understood. The small GTPases Rab27a and Rab27b and their effectors, Slp4 and Slac2b, control exosome secretion at different steps by regulating the peripheral localization, retent...

    Matias Ostrowski, Nuno B. Carmo, Sophie Krumeich, Isabelle Fanget… in Nature Cell Biology (2010)

  7. Article

    Open Access

    A multi-Fc-species system for recombinant antibody production

    Genomic, transcriptomic and proteomic projects often suffer from a lack of functional validation creating a strong demand for specific and versatile antibodies. Antibody phage display represents an attractive ...

    Sandrine Moutel, Ahmed El Marjou, Ole Vielemeyer, Clément Nizak… in BMC Biotechnology (2009)

    Download PDF (3864 KB) View Article

  8. No Access

    Article

    MHC class II dimer of dimers

    Hidde Ploegh, Philippe Benaroch in Nature (1993)

  9. No Access

    Article

    Tetramer data reinterpreted

    Philippe Benaroch, Sudhir Krishna, Shiv Pillai in Nature (1993)

  10. No Access

    Article

    Tetrameric cell-surface MHC class I molecules

    PURIFIED major histocompatibility complex (MHC) class I molecules have been studied at high resolution by X-ray crystallography1; the structure is a complex of a single heavy chain, β2-microglobulin light chain a...

    Sudhir Krishna, Philippe Benaroch, Shiv Pillai in Nature (1992)