5 Result(s)
within
Philip Bejon
Medicine & Public Health
Infectious Diseases
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Article
Open AccessDistinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected
Cumulative malaria parasite exposure in endemic regions often results in the acquisition of partial immunity and asymptomatic infections. There is limited information on how host-parasite interactions mediate ...
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Article
Open AccessEndemic chikungunya fever in Kenyan children: a prospective cohort study
Chikungunya fever (CHIKF) was first described in Tanzania in 1952. Several epidemics including East Africa have occurred, but there are no descriptions of longitudinal surveillance of endemic disease. Here, we...
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Article
Open AccessTrends in bednet ownership and usage, and the effect of bednets on malaria hospitalization in the Kilifi Health and Demographic Surveillance System (KHDSS): 2008–2015
Use of bednets reduces malaria morbidity and mortality. In Kilifi, Kenya, there was a mass distribution of free nets to children < 5 years in 2006. In 2009, a new policy was implemented to offer bednets to pre...
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Article
Open AccessPlasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure
The PfEMP1 family of Plasmodium falciparum antigens play a key role in pathogenesis of severe malaria through their insertion into the surface of parasite infected erythrocytes, and adhesion to host cells. Previo...
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Article
Open AccessUse of an automated blood culture system (BD BACTEC™) for diagnosis of prosthetic joint infections: easy and fast
For the diagnosis of prosthetic joint infection (PJI) automated BACTEC™ blood culture bottle methods have comparable sensitivity, specificity and a shorter time to positivity than traditional cooked meat enric...
