Skip to main content

3 Result(s)

within Petros Tsantoulis Remove this filter Cancer Research Remove this filter

and
Your search also matched 1 preview-only Content is preview-only when you or your institution have not yet subscribed to it.

By making our abstracts and previews universally accessible we help you purchase only the content that is relevant to you. results, e.g.

Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer

Include preview-only content

  1. Article

    Open Access

    Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer

    The consensus molecular subtype (CMS) classification of colorectal cancer is based on bulk transcriptomics. The underlying epithelial cell diversity remains unclear. We analyzed 373,058 single-cell transcripto...

    Ignasius Joanito, Pratyaksha Wirapati, Nancy Zhao, Zahid Nawaz… in Nature Genetics (2022)

    Download PDF (23425 KB) View Article

  2. Article

    Open Access

    RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia

    Despite recent advances in acute myeloid leukemia (AML) molecular characterization and targeted therapies, a majority of AML cases still lack therapeutically actionable targets. In 127 AML cases with unmet the...

    Justine Decroocq, Rudy Birsen, Camille Montersino, Prasad Chaskar, Jordi Mano… in Leukemia (2022)

    Download PDF (4864 KB) View Article

  3. Article

    Open Access

    Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection

    A better understanding of the molecular profile of anal squamous cell carcinomas (ASCCs) is necessary to consider new therapeutic approaches, and the identification of prognostic and predictive factors for res...

    Wulfran Cacheux, Etienne Rouleau, Adrien Briaux… in British Journal of Cancer (2016)

    Download PDF (356 KB) View Article