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Article
Open AccessPost-therapeutic circulating tumor cell-associated white blood cell clusters predict poor survival in patients with advanced driver gene-negative non-small cell lung cancer
This study aimed to investigate the clinical utility of diverse aneuploid circulating tumor cell (CTC) subtypes and particularly CTC-associated white blood cell (CTC-WBC) clusters in predicting treatment respo...
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Article
Formalin pigment artifact deposition in autopsy tissue: predisposing factors, patterns of distribution and methods for removal
Formalin pigment deposition is a known artifact of autopsy histology, often anecdotally associated with decomposition of bodies. However, there is minimal data within the forensic literature demonstrating an a...
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Article
Open AccessVimentin expression in circulating tumor cells (CTCs) associated with liver metastases predicts poor progression-free survival in patients with advanced lung cancer
To investigate the presence of vimentin expression in CTCs and its clinical relevance in patients with advanced lung cancer.
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Article
The characteristics of all-terrain vehicle (ATV)-related deaths: A forensic autopsy data-based study
Using forensic autopsy-based data from a regional medical examiner office in the midwestern U.S. with a mixed small urban-rural population, we describe the characteristics of all-terrain vehicle (ATV)-related ...
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Article
Open AccessCirculating tumor cells with karyoty** as a novel biomarker for diagnosis and treatment of nasopharyngeal carcinoma
Circulating tumor cells (CTCs) have been considered great clinical significance in various cancers. However, it remains unknown that how is the role of CTCs in patients with nasopharyngeal carcinoma (NPC). We ...
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Article
Lower Extremity Bypass Using Bovine Carotid Artery Graft (Artegraft): An Analysis of 124 Cases with Long-Term Results
Although biological grafts have been utilized as a vascular conduit in leg bypass for many years, reports of a bovine carotid artery graft (BCAG) in lower extremity revascularization have been scarce. This stu...
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Article
Contemporary Management of Patients with Concomitant Coronary and Carotid Artery Disease
The ideal management of concomitant carotid and coronary artery occlusive disease remains elusive. Although researchers have advocated the potential benefits of varying treatment strategies based on either con...
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Article
Open AccessComprehensive in situ co-detection of aneuploid circulating endothelial and tumor cells
Conventional circulating tumor cell (CTC) detection strategies rely on cell surface marker EpCAM and intracellular cytokeratins (CKs) for isolation and identification, respectively. Application of such methods...
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Article
Open AccessErratum to: Integrated EpCAM-independent subtraction enrichment and iFISH strategies to detect and classify disseminated and circulating tumors cells
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Article
Open AccessIntegrated EpCAM-independent subtraction enrichment and iFISH strategies to detect and classify disseminated and circulating tumors cells
Application of tumor cell surface adhesion molecule EpCAM-dependent antibody capture, and intracellular cytokeratins (CKs)-dependent immunostaining strategies to detect disseminated or circulating tumor cells ...
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Article
Erratum to: Reliability of Postmortem Fentanyl Concentrations in Determining the Cause of Death
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Article
Open AccessSevere pulmonic valve regurgitation due to histoplasma endocarditis
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Article
Determination of EGFR mutations in single cells microdissected from enriched lung tumor cells in peripheral blood
A minimally invasive and repeatable approach for real-time epidermal growth factor receptor (EGFR) mutation surveillance would be highly beneficial for individualized therapy of late stage lung cancer patients wh...
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Article
Reliability of Postmortem Fentanyl Concentrations in Determining the Cause of Death
Transdermal fentanyl, an opioid used for management of marked pain, also is abused and may cause death.
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Chapter
Pulmonary Embolism and SVC Syndrome
Pulmonary embolism (PE) is a potentially fatal condition caused by embolic occlusion of the pulmonary artery or one of its branches due to thrombotic material that has traveled through the bloodstream from els...
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Article
Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis
MicroRNAs (miRNAs) are involved in cancer pathogenesis, apoptosis, and cell growth, thereby functioning as tumor suppressors or oncogenes. However, expression alterations and roles of these miRNAs in pancreati...
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Chapter
Endovascular Treatment of Abdominal Aortic Aneurysms
Aneurysmal disease of the aorta affects 5% of the adult population in the United States and abdominal aortic aneurysms (AAA) are responsible for approximately 20,000 deaths per year, making it the 10th most co...
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Article
Open Access1016 Increased sensitivity for detection of intra-cardiac thrombus using phase sensitive inversion recovery (PSIR) late enhancement techniques for combined myocardial scar and thrombus imaging
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Article
Recent Advances in Molecular Mechanisms of Abdominal Aortic Aneurysm Formation
Abdominal aortic aneurysm (AAA) is an increasingly common clinical condition with fatal implications. It is associated with advanced age, male gender, cigarette smoking, atherosclerosis, hypertension, and gene...
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Article
Comparison of AngioJet Rheolytic Pharmacomechanical Thrombectomy versus AngioJet Rheolytic Thrombectomy in a Porcine Peripheral Arterial Model
Rheolytic thrombectomy using the AngioJet catheter for arterial thrombosis has been shown to be effective in restoring blood flow. Additional infusion of thrombolytic agents via the AngioJet catheter results i...
