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Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer

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  1. Article

    Open Access

    RETRACTED ARTICLE: Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression

    Hepatocellular carcinoma (HCC) remains difficult to cure due to lack of effective treatment and the molecular mechanisms are complex and not completely understood. In this study, We investigated the role of CD...

    Yitao Wang, **an Qin, Tao Guo, Pengpeng Liu in Journal of Experimental & Clinical Cancer … (2017)

  2. Article

    Open Access

    Upregulation of DARS2 by HBV promotes hepatocarcinogenesis through the miR-30e-5p/MAPK/NFAT5 pathway

    Infection with the hepatitis B virus (HBV) is closely associated with the development of hepatocellular carcinoma (HCC). The osmoregulatory transcription factor nuclear factor of activated T-cells 5 (NFAT5) ha...

    **an Qin, Changsheng Li, Tao Guo, **g Chen in Journal of Experimental & Clinical Cancer … (2017)

  3. Article

    Open Access

    Retraction Note: Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression

    The Editor-in-Chief has retracted this article [1] due to concerns about the figures. In Figure 3C, the images from the colony formation assays of all cell lines, excluding the control for the HCCLM9 cell line...

    Yitao Wang, **an Qin, Tao Guo, Pengpeng Liu in Journal of Experimental & Clinical Cancer … (2019)

  4. Article

    Open Access

    LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer

    Long Interspersed Nuclear Element-1 (LINE-1, L1) is increasingly regarded as a genetic risk for lung cancer. Transcriptionally active LINE-1 forms a L1-gene chimeric transcript (LCTs), through somatic L1 retro...

    Zeguo Sun, Rui Zhang, **ao Zhang, Yifei Sun, Pengpeng Liu in Molecular Cancer (2022)

  5. Article

    Open Access

    COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma

    Deletions of chromosome 17p, where TP53 gene locates, are the most frequent chromosome alterations in human cancers and associated with poor outcomes in patients. Our previous work suggested that there were p53–i...

    Lu Qi, **angyu Pan, Xuelan Chen, Pengpeng Liu, Mei Chen, Qi Zhang in Oncogenesis (2023)

  6. Article

    Open Access

    Lymphangiogenesis in gastric cancer: function and mechanism

    Increased lymphangiogenesis and lymph node (LN) metastasis are thought to be important steps in cancer metastasis, and are associated with patient's poor prognosis. There is increasing evidence that the lympha...

    Pengpeng Liu, **’an Ding, Chenyu Sun, Shuya Chen in European Journal of Medical Research (2023)

  7. Article

    Open Access

    Mechanisms and biomarkers of immune-related adverse events in gastric cancer

    Immune-checkpoint inhibitors (ICIs), different from traditional cancer treatment models, have shown unprecedented anti-tumor effects in the past decade, greatly improving the prognosis of many malignant tumors...

    **’an Ding, Pengpeng Liu, Lingjiao Meng, Qun Zhao in European Journal of Medical Research (2023)

  8. Article

    Open Access

    Targeted sequencing of DNA/RNA combined with radiomics predicts lymph node metastasis of papillary thyroid carcinoma

    The aim of our study is to find a better way to identify a group of papillary thyroid carcinoma (PTC) with more aggressive behaviors and to provide a prediction model for lymph node metastasis to assist in cli...

    Runjiao Zhang, Linfei Hu, Yanan Cheng, Luchen Chang, Li Dong, Lei Han in Cancer Imaging (2024)