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  1. No Access

    Article

    Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer

    We previously identified that the development of early-stage myeloid-derived suppressor cells (eMDSCs) in breast cancer with high IL-6 (IL-6high) expression was correlated with the SOCS3 deficiency-dependent hype...

    Mengmeng Jiang, Wenwen Zhang, Rui Zhang, Pengpeng Liu, Yingnan Ye, Wenwen Yu… in Oncogene (2020)

  2. No Access

    Article

    BCL-2 isoform β promotes angiogenesis by TRiC-mediated upregulation of VEGF-A in lymphoma

    Bcl-2 (B-cell lymphoma 2), the first identified anti-apoptosis factor, encodes two transcripts, the long isoform α and the short isoform β. The current understanding of the Bcl-2 function mainly focuses on Bcl-2α...

    **aohang Hang, Lei Zhao, Baohong Wu, Shujun Li, Pengpeng Liu, **g Xu… in Oncogene (2022)

  3. Article

    Open Access

    COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma

    Deletions of chromosome 17p, where TP53 gene locates, are the most frequent chromosome alterations in human cancers and associated with poor outcomes in patients. Our previous work suggested that there were p53–i...

    Lu Qi, **angyu Pan, Xuelan Chen, Pengpeng Liu, Mei Chen, Qi Zhang… in Oncogenesis (2023)

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  4. No Access

    Article

    DNMT3AR882H accelerates angioimmunoblastic T-cell lymphoma in mice

    DNA methylation-related genes, including TET2, IDH2, and DNMT3A are highly frequently mutated in angioimmunoblastic T-cell lymphoma (AITL), an aggressive malignancy of T follicular helper (Tfh) cells associated w...

    Jianan Zheng, Zhongwang Wang, **angyu Pan, Zhixin Zhang, He Li, **ntong Deng… in Oncogene (2023)

  5. Article

    Open Access

    Lymphangiogenesis in gastric cancer: function and mechanism

    Increased lymphangiogenesis and lymph node (LN) metastasis are thought to be important steps in cancer metastasis, and are associated with patient's poor prognosis. There is increasing evidence that the lympha...

    Pengpeng Liu, **’an Ding, Chenyu Sun, Shuya Chen… in European Journal of Medical Research (2023)

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  6. Article

    Open Access

    Mechanisms and biomarkers of immune-related adverse events in gastric cancer

    Immune-checkpoint inhibitors (ICIs), different from traditional cancer treatment models, have shown unprecedented anti-tumor effects in the past decade, greatly improving the prognosis of many malignant tumors...

    **’an Ding, Pengpeng Liu, Lingjiao Meng, Qun Zhao in European Journal of Medical Research (2023)

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