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  1. No Access

    Article

    DNMT3AR882H accelerates angioimmunoblastic T-cell lymphoma in mice

    DNA methylation-related genes, including TET2, IDH2, and DNMT3A are highly frequently mutated in angioimmunoblastic T-cell lymphoma (AITL), an aggressive malignancy of T follicular helper (Tfh) cells associated w...

    Jianan Zheng, Zhongwang Wang, **angyu Pan, Zhixin Zhang, He Li, **ntong Deng… in Oncogene (2023)

  2. Article

    Open Access

    COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma

    Deletions of chromosome 17p, where TP53 gene locates, are the most frequent chromosome alterations in human cancers and associated with poor outcomes in patients. Our previous work suggested that there were p53–i...

    Lu Qi, **angyu Pan, Xuelan Chen, Pengpeng Liu, Mei Chen, Qi Zhang… in Oncogenesis (2023)

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  3. No Access

    Article

    BCL-2 isoform β promotes angiogenesis by TRiC-mediated upregulation of VEGF-A in lymphoma

    Bcl-2 (B-cell lymphoma 2), the first identified anti-apoptosis factor, encodes two transcripts, the long isoform α and the short isoform β. The current understanding of the Bcl-2 function mainly focuses on Bcl-2α...

    **aohang Hang, Lei Zhao, Baohong Wu, Shujun Li, Pengpeng Liu, **g Xu… in Oncogene (2022)

  4. No Access

    Article

    LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria

    The accumulation of deleterious mitochondrial DNA (∆mtDNA) causes inherited mitochondrial diseases and ageing-associated decline in mitochondrial functions such as oxidative phosphorylation. Following mitochon...

    Qiyuan Yang, Pengpeng Liu, Nadine S. Anderson, Tomer Shpilka… in Nature Cell Biology (2022)

  5. No Access

    Article

    Long non-coding RNA A1BG-AS1 promotes tumorigenesis in breast cancer by sponging microRNA-485-5p and consequently increasing expression of FLOT1 expression

    The dysregulated long non-coding RNA A1BG antisense RNA 1 (A1BG-AS1) has been implicated in the oncogenicity of hepatocellular carcinoma. Using reverse transcription quantitative polymerase chain reaction in t...

    Shibin Cai, Yi Zhou, Ying Pan, Pengpeng Liu, Kaijie Yu, Shuzheng Chen in Human Cell (2021)

  6. No Access

    Article

    LINC00662 promotes hepatocellular carcinoma progression via altering genomic methylation profiles

    The identification of viability-associated long noncoding RNAs (lncRNAs) is a means of uncovering therapeutic approaches for hepatocellular carcinoma (HCC). In addition, aberrant genome-wide hypomethylation ha...

    Tao Guo, Cheng Gong, ** Wu, Shyue-Fang Battaglia-Hsu… in Cell Death & Differentiation (2020)

  7. No Access

    Article

    Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer

    We previously identified that the development of early-stage myeloid-derived suppressor cells (eMDSCs) in breast cancer with high IL-6 (IL-6high) expression was correlated with the SOCS3 deficiency-dependent hype...

    Mengmeng Jiang, Wenwen Zhang, Rui Zhang, Pengpeng Liu, Yingnan Ye, Wenwen Yu… in Oncogene (2020)

  8. Article

    Regulation of transcriptionally active genes via the catalytically inactive Cas9 in C. elegans and D. rerio

    Lijiang Long, Hong Guo, Di Yao, Kai **ong, Yongjun Li, Pengpeng Liu… in Cell Research (2015)

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  9. Article

    Heritable/conditional genome editing in C. elegans using a CRISPR-Cas9 feeding system

    Pengpeng Liu, Lijiang Long, Kai **ong, Bo Yu, Nannan Chang, **g-Wei **ong… in Cell Research (2014)

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  10. Article

    mir-35 is involved in intestine cell G1/S transition and germ cell proliferation in C. elegans

    MicroRNA (miRNA) regulates gene expression in many cellular events, yet functions of only a few miRNAs are known in C. elegans. We analyzed the function of mir-35-41 unique to the worm, and show here that mir-35 ...

    Min Liu, Pengpeng Liu, Li Zhang, Qingchun Cai, Ge Gao, Wenxia Zhang… in Cell Research (2011)

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