4 Result(s)

Article

NmeCas9 is an intrinsically high-fidelity genome-editing platform

The development of CRISPR genome editing has transformed biomedical research. Most applications reported thus far rely upon the Cas9 protein from Streptococcus pyogenes SF370 (SpyCas9). With many RNA guides, wild...

Nadia Amrani, **n D. Gao, Pengpeng Liu, Alireza Edraki, Aamir Mir… in Genome Biology (2018)

Article

Regulation of transcriptionally active genes via the catalytically inactive Cas9 in C. elegans and D. rerio

Lijiang Long, Hong Guo, Di Yao, Kai **ong, Yongjun Li, Pengpeng Liu… in Cell Research (2015)

Article

Heritable/conditional genome editing in C. elegans using a CRISPR-Cas9 feeding system

Pengpeng Liu, Lijiang Long, Kai **ong, Bo Yu, Nannan Chang, **g-Wei **ong… in Cell Research (2014)

Article

mir-35 is involved in intestine cell G1/S transition and germ cell proliferation in C. elegans

MicroRNA (miRNA) regulates gene expression in many cellular events, yet functions of only a few miRNAs are known in C. elegans. We analyzed the function of mir-35-41 unique to the worm, and show here that mir-35 ...

Min Liu, Pengpeng Liu, Li Zhang, Qingchun Cai, Ge Gao, Wenxia Zhang… in Cell Research (2011)