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Article
Bone marrow mesenchymal stem cells-derived exosomes containing miR-539-5p inhibit pyroptosis through NLRP3/caspase-1 signalling to alleviate inflammatory bowel disease
Exosomes derived from bone mesenchymal stem cells (BMSCs) are potential candidates for inflammatory bowel disease (IBD) treatment. The present study investigated the therapeutic effect and potential mechanism ...
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Article
CircIFFO1 suppresses tumor growth and metastasis of cutaneous squamous cell carcinoma by targeting the miR-424-5p/NFIB axis
Cutaneous squamous cell carcinoma (CSCC) is a severe malignancy derived from the skin. Circular RNAs (circRNAs) play an important role in the pathological process of many malignant tumors. Moreover, circIFFO1 ...
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Chapter and Conference Paper
Numerical Study on Fracture Formation and Propagation Law in the Perforating Process Based on FEM-SPH Coupling
In the exploration and development of oil and gas wells, perforation completion is the most commonly applied method of well completion. The formation of fracture networks near the wellbore during perforation i...
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Article
Analysis of FEM-SPH coupling for perforation penetration variation under different geology-engineering conditions
Fracturing fluid flow and fracture network formation are greatly affected by perforation penetration. It is essential to predict perforation penetration in order to optimize the parameters involved in perforat...