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Open AccessResearch on the dynamic tensile characteristics and surface crack evolution of coal under impact loading
The tensile properties of coal under dynamic loading are important mechanical characteristics of coal and are highly important for controlling coal rock stability under impact loading conditions, selecting bla...
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Article
A decomposition-based multi-objective evolutionary algorithm with Q-learning for adaptive operator selection
In the past few decades, many multi-objective evolution algorithms (MOEAs) have been proposed, often emphasizing a single crossover operator, which has a significant impact on the algorithm’s performance. This...
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Article
Open AccessAssociations between smoking, sex steroid hormones, trouble slee**, and depression among U.S. adults: a cross-sectional study from NHANES (2013–2016)
Dose-response and nonlinear relationships of cigarette exposure with sleep disturbances and depression are warranted, and the potential mechanism of sex hormones in such associations remains unclear.
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Article
Late Mesoproterozoic to Early Neoproterozoic Tectonic Evolution of the SW Yangtze Block, South China: Evidence from U-Pb Geochronology and Lu-Hf Isotopes of Detrital Zircons from Sedimentary Rocks
In situ zircon U-Pb geochronological and Lu-Hf isotope studies of detrital zircons from Late Mesoproterozoic to Early Neoproterozoic sedimentary units on the southwestern margin of the Yangtze Block have importan...
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Article
Open AccessGlycolysis inhibition induces anti-tumor central memory CD8+T cell differentiation upon combination with microwave ablation therapy
Minimally invasive thermal therapy is a successful alternative treatment to surgery in solid tumors with high complete ablation rates, however, tumor recurrence remains a concern. Central memory CD8+ T cells (TCM
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Article
Open AccessOsEXPA7 Encoding an Expansin Affects Grain Size and Quality Traits in Rice (Oryza sativa L.)
Yield and quality are the two most important traits in crop breeding. Exploring the regulatory mechanisms that affect both yield and quality traits is of great significance for understanding the molecular gene...
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Article
Open AccessEndothelial EGLN3-PKM2 signaling induces the formation of acute astrocytic barrier to alleviate immune cell infiltration after subarachnoid hemorrhage
Most subarachnoid hemorrhage (SAH) patients have no obvious hematoma lesions but exhibit blood–brain barrier dysfunction and vasogenic brain edema. However, there is a few days between blood‒brain barrier dysf...
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Article
Climatic precipitation efficiency and its dependence on environmental factors over the Sichuan Basin and adjacent regions, Southwest China
Based on satellite observation and reanalysis data, basic features of cloud water and precipitation and the dependence of precipitation efficiency (PE) on environmental factors over the Sichuan Basin and adjac...
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Article
Open AccessIdentification of MYCN non-amplified neuroblastoma subgroups points towards molecular signatures for precision prognosis and therapy stratification
Despite the extensive study of MYCN-amplified neuroblastomas, there is a significant unmet clinical need in MYCN non-amplified cases. In particular, the extent of heterogeneity within the MYCN non-amplified popul...
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Article
Low-Temperature Plasma Modification of Lignin-Derived Carbon Solid Acid Catalyst for Catalytic Production of 5-HMF
Sulfonated carbon catalysts exhibit superior catalytic performance for production of biobased chemicals, but the catalyst preparation approaches are still suffered from high corrosion and possible pollution ri...
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Open AccessTIMP-3 Alleviates White Matter Injury After Subarachnoid Hemorrhage in Mice by Promoting Oligodendrocyte Precursor Cell Maturation
Subarachnoid hemorrhage (SAH) is associated with high mortality and disability rates, and secondary white matter injury is an important cause of poor prognosis. However, whether brain capillary pericytes can d...
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Article
Effects of Detritus Treatments on Soil Microbial Community Composition, Structure and Nutrient Limitation in a Subtropical Karst Ecosystem
Detritus inputs and removal strongly influence soil carbon (C), nitrogen (N), and phosphorus (P) as well as soil microbial communities and resource limitations. Here, we characterized soil microbial communitie...
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Article
Open AccessAllantoate Amidohydrolase OsAAH is Essential for Preharvest Sprouting Resistance in Rice
Preharvest sprouting (PHS) is an undesirable trait that decreases yield and quality in rice production. Understanding the genes and regulatory mechanisms underlying PHS is of great significance for breeding PH...
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Article
Molecular epidemiology and resistance mechanisms of tigecycline-non-susceptible Acinetobacter baumannii isolated from a tertiary care hospital in Chongqing, China
We studied 34 isolates of Tigecycline-Non-Susceptible A. baumannii (TNAB) obtained from clinical specimens at a large tertiary care hospital in Chongqing, China. These 34 strains belonged to 8 different clones in...
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Article
Open AccessGadd45g insufficiency drives the pathogenesis of myeloproliferative neoplasms
Despite the identification of driver mutations leading to the initiation of myeloproliferative neoplasms (MPNs), the molecular pathogenesis of MPNs remains incompletely understood. Here, we demonstrate that gr...
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Article
Chloroplast Genome Sequence and Phylogenetic Analysis of Medicinal Plant Pinellia ternata
Pinellia ternata, as one of the traditional Chinese medicines, has a significant effect on eliminating dampness, stop** vomiting and calm the adverse-rising energy. There are few researches on the structural ch...
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Article
Identification and virus-induced gene silencing (VIGS) analysis of methyltransferase affecting tomato (Solanum lycopersicum) fruit ripening
Six methyltransferase genes affecting tomato fruit ripening were identified through genome-wide screening, VIGS assay, and expression pattern analysis. The data provide the basis for understanding new mechanis...
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Article
Effects of Gelsemium elegans extract on the red fire ant: disruption of peritrophic membrane integrity and alteration of gut microbial diversity, composition, and function
Gelsemium elegans Benth. (Loganiaceae), also known as heartbreak herb, can be used in the manufacture of herbal medicines. Insecticidal activity has also been found and can be used to develop botanical insecticid...
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Open AccessAnalyzing the correlation between gastroesophageal reflux disease and anxiety and depression based on ordered logistic regression
Numerous studies have indicated a connection between psychiatric symptoms, specifically anxiety and depression, and gastroesophageal reflux. However, the precise nature of the link between the severity of gast...
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Article
Open AccessLactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression
Abundant macrophage infiltration and altered tumor metabolism are two key hallmarks of glioblastoma. By screening a cluster of metabolic small-molecule compounds, we show that inhibiting glioblastoma cell glyc...
