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  1. Article

    Open Access

    Influence of baseline arterial stiffness on effects of intensive compared with standard blood pressure control: a post hoc analysis of the STEP trial

    The benefits and risks of intensive versus standard systolic blood pressure (SBP) treatment in older patients with arterial stiffness (AS) remains unclear. This study aims to investigate the interaction betwee...

    Qirui Song, Qianhui Ling, **g**g Bai, Hongwei Zhang, Peili Bu, Fang Chen in BMC Medicine (2022)

  2. Article

    Open Access

    Effect of fecal microbiota transplantation on primary hypertension and the underlying mechanism of gut microbiome restoration: protocol of a randomized, blinded, placebo-controlled study

    Hypertension is currently the leading modifiable cause of global morbidity and mortality, leading to substantial health and financial burdens. Although multiple studies of management models and innovative ther...

    Luyun Fan, Jie Ren, Youren Chen, Yang Wang, Zihong Guo, Peili Bu, **feng Yang in Trials (2022)

  3. Article

    Open Access

    Correction to: Sirtuin 3 deficiency aggravates contrast-induced acute kidney injury

    Qinghai Zhang, Xun Liu, Na li, Jihong Zhang in Journal of Translational Medicine (2022)

  4. No Access

    Article

    Sirt3 promotes sensitivity to sunitinib-induced cardiotoxicity via inhibition of GTSP1/JNK/autophagy pathway in vivo and in vitro

    Sunitinib malate is a multi-targeted tyrosine kinase inhibitor used extensively for treatment of human tumors. However, cardiovascular adverse effects of sunitinib limit its clinical use. It is pivotal to eluc...

    Yi Yang, Na Li, Tongshuai Chen, Chunmei Zhang, **gyuan Li in Archives of Toxicology (2019)

  5. Article

    Open Access

    Sirtuin 3 deficiency aggravates contrast-induced acute kidney injury

    Sirtuin 3 (Sirt3) is a key regulator of energy metabolism and oxidative stress. To investigate the role of Sirt3 in contrast-induced acute kidney injury (CIAKI), we established the model both in vivo and in vi...

    Qinghai Zhang, Xun Liu, Na li, Jihong Zhang in Journal of Translational Medicine (2018)