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    Anti-CENP-B and anti-TOPO-1-containing sera from systemic sclerosis-related diseases with Raynaud’s phenomenon induce vascular endothelial cell senescence not via classical p53-p21 pathway

    Raynaud’s phenomenon (RP) is the earliest and most common clinical manifestation in patients with systemic sclerosis (SSc) and its related diseases containing anti-TOPO-1 and/or anti-CENP-B autoantibodies in t...

    Chieh-Yu Shen, Ko-Jen Li, Pei-Hsuan Lai, Chia-Li Yu… in Clinical Rheumatology (2018)