13 Result(s)
within
Paul M. O’Byrne
English
Immunology
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Article
Open AccessThe cost-effectiveness of as-needed budesonide-formoterol versus low-dose inhaled corticosteroid maintenance therapy in patients with mild asthma in Canada
The Global Initiative for Asthma recommends the use of as-needed low-dose inhaled corticosteroid (ICS)-formoterol as a preferred controller therapy for patients with mild asthma. These recommendations were bas...
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Article
Open AccessUse of a vibrating mesh nebulizer for allergen challenge
Allergen inhalation tests are a valuable research tool. The allergen dose producing an early asthmatic response (EAR) can be predicted from methacholine responsiveness and allergen skin test endpoint (STE). Th...
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Article
Open AccessInterleukin-25 and eosinophils progenitor cell mobilization in allergic asthma
Eosinophil-lineage committed progenitor cells (EoP) migrate from the bone marrow and differentiate locally to provide an ongoing source of mature eosinophils in asthmatic inflammatory responses in the airways....
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Article
Open AccessAllerGen’s 8th research conference
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Article
Open AccessTherapeutic interventions in severe asthma
The present paper addresses severe asthma which is limited to 5-10% of the overall population of asthmatics. However, it accounts for 50% or more of socials costs of the disease, as it is responsible for hospi...
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Article
Open AccessProceedings of the Canadian society of allergy and clinical immunology annual scientific meeting 2015
A1 Role of fibrocytes in allergic rhinitis
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Article
Open AccessBlood biomarkers of the late phase asthmatic response using RNA-Seq
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Article
Open AccessTh17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response
The imbalance between Th17 and Treg cells has been studied in various diseases including allergic asthma but their roles have not been fully understood in the development of the late phase asthmatic response.
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Article
Open AccessTh17/Treg ratio derived using DNA methylation analysis discriminates allergen-induced early from dual asthmatic responses
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Article
The pharmacological modulation of allergen-induced asthma
Aeroallergens are the most common triggers for the development of asthma. Recent birth cohort studies have identified viral infections occurring against a background of aeroallergen sensitization as a potent r...
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Article
Open AccessFunctional genomics of the peripheral blood response to allergen inhalation challenge
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Chapter
Mechanisms and Management of Exercise-Induced Bronchoconstriction
The term “exercise-induced asthma” has been used to describe the transient narrowing of the airways and the subsequent increase in airway resistance, which can occur during, though more commonly following, vig...
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Chapter
Future Trends in the Use of Corticosteroids in Asthma
Corticosteroids have been used to treat a variety of airway diseases since the early 1950s, following an initial study of Carryer et al. [1], who reported the benefits of oral cortisone on ragweed pollen-induc...
