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A Novel Strategy for Continuation ECT in Geriatric Depression: Phase 2 of the PRIDE Study
In this study, the authors evaluated the efficacy and tolerability of continuation electroconvulsive therapy plus medication when compared to medication alone in depressed older adults from phase 2 of a random...
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Article
Open AccessInterleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site
Neuroinflammation, typified by elevated levels of interleukin-1 (IL-1) α and β, and deficits in proteostasis, characterized by accumulation of polyubiquitinated proteins and other aggregates, are associated wi...