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Article

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models

Melanoma is the most deadly form of skin cancer. Expression of oncogenic BRAF or NRAS, which are frequently mutated in human melanomas, promote the formation of nevi but are not sufficient for tumorigenesis. Even...

Jennifer Yen, Richard M White, David C Wedge, Peter Van Loo… in Genome Biology (2013)