4 Result(s)
within
Patrick M. Kochanek
Life Sciences
-
Article
Open AccessNeuronal RBM5 modulates cell signaling responses to traumatic and hypoxic-ischemic injury in a sex-dependent manner
It is not clear if inhibiting the pro-death gene RNA binding motif 5 (RBM5) is neuroprotective in isolated primary neurons or if it regulates cell survival in a sex-dependent manner. Here we established sex-di...
-
Protocol
Oxidative Lipidomics of Apoptosis: Quantitative Assessment of Phospholipid Hydroperoxides in Cells and Tissues
Oxidized phospholipids play essential roles in execution of mitochondrial stage of apoptosis and clearance of apoptotic cells. The identification and quantification of oxidized phospholipids generated during a...
-
Chapter
The Regional Cerebral Blood Flow Response to Cortical Microelectrode Insertion is Neutrophil Dependent
Tissue blood flow measurements using the H2-clearance technique with implanted polarographic microelectrodes was described by Aukland et al. in 1964 (1). The H2-clearance technique has important advantages over o...
-
Chapter
Platelet Activating Factor Antagonists do not Alter Normal Cerebral Blood Flow or Cerebral Oxygen Consumption
Platelet activating factor (PAF), (1-o-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine) an endogenous lipid, is involved in the cerebrovascular response to ischemia (1–5). It potently vasoconstricts (6,7), incr...
