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Reversible S-nitrosylation in an engineered azurin

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  1. Article

    Open Access

    Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

    Despite recent success in computational design of structured cyclic peptides, de novo design of cyclic peptides that bind to any protein functional site remains difficult. To address this challenge, we develop...

    Parisa Hosseinzadeh, Paris R. Watson, Timothy W. Craven… in Nature Communications (2021)

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  2. Article

    Open Access

    Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor

    Despite the increasing number of GPCR structures and recent advances in peptide design, the development of efficient technologies allowing rational design of high-affinity peptide ligands for single GPCRs rema...

    Edin Muratspahić, Kristine Deibler, Jianming Han, Nataša Tomašević… in Nature Communications (2023)

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