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  1. Article

    Open Access

    Causal analysis of positive Reaction Systems

    Cause/effect analysis of complex systems is instrumental in better understanding many natural phenomena. Moreover, formal analysis requires the availability of suitable abstract computational models that someh...

    Linda Brodo, Roberto Bruni, Moreno Falaschi in International Journal on Software Tools fo… (2024)

  2. No Access

    Chapter and Conference Paper

    Validation of a Simulation Algorithm for Safety-Critical Human Multitasking

    Multitasking has become surprisingly present in our life. This is mostly due to the fact that nowadays most of our activities involve the interaction with one or more devices. In such a context the brain mecha...

    Giovanna Broccia, Paolo Milazzo in Formal Methods. FM 2019 International Work… (2020)

  3. Article

    Formal modeling and analysis of safety-critical human multitasking

    When a person is concurrently interacting with different systems, the amount of cognitive resources required (cognitive load) could be too high and might prevent some tasks from being completed. When such huma...

    Giovanna Broccia, Paolo Milazzo in Innovations in Systems and Software Engine… (2019)

  4. No Access

    Chapter and Conference Paper

    Multiset Patterns and Their Application to Dynamic Causalities in Membrane Systems

    In this paper we investigate dynamic causalities in membrane systems by proposing the concept of “predictor”, originally defined in the context of Ehrenfeucht and Rozemberg’s reaction systems. The goal is to c...

    Roberto Barbuti, Roberta Gori, Paolo Milazzo in Membrane Computing (2018)

  5. No Access

    Chapter and Conference Paper

    An Executable Formal Framework for Safety-Critical Human Multitasking

    When a person is concurrently interacting with different systems, the amount of cognitive resources required (cognitive load) could be too high and might prevent some tasks from being completed. When such huma...

    Giovanna Broccia, Paolo Milazzo, Peter Csaba Ölveczky in NASA Formal Methods (2018)

  6. No Access

    Chapter and Conference Paper

    Formalizing a Notion of Concentration Robustness for Biochemical Networks

    The main goal of systems biology is to understand the dynamical properties of biological systems by investigating the interactions among the components of a biological system. In this work, we focus on the rob...

    Lucia Nasti, Roberta Gori, Paolo Milazzo in Software Technologies: Applications and Fo… (2018)

  7. No Access

    Chapter and Conference Paper

    Applications of P Systems in Population Biology and Ecology: The Cases of MPP and APP Systems

    We describe two extensions of P systems for the modelling of populations and ecosystems. They are the Minimal Probabilistic P systems (MPP systems) and the Attributed Probabilistic P systems (APP systems). We ...

    Roberto Barbuti, Pasquale Bove, Paolo Milazzo, Giovanni Pardini in Membrane Computing (2017)

  8. No Access

    Book and Conference Proceedings

    Software Technologies: Applications and Foundations

    STAF 2016 Collocated Workshops: DataMod, GCM, HOFM, MELO, SEMS, VeryComp, Vienna Austria, July 4-8, 2016, Revised Selected Papers

    Paolo Milazzo, Dániel Varró in Lecture Notes in Computer Science (2016)

  9. No Access

    Chapter and Conference Paper

    A High-Level Model Checking Language with Compile-Time Pruning of Local Variables

    Among Model Checking tools, the behaviour of a system is often formalized as a transition system with atomic propositions associated with states (Kripke structure). In current modelling languages, transitions are...

    Giovanni Pardini, Paolo Milazzo in Software Technologies: Applications and Foundations (2016)

  10. No Access

    Chapter and Conference Paper

    A Mathematical Model for Assessing KRAS Mutation Effect on Monoclonal Antibody Treatment of Colorectal Cancer

    The most challenging task in colorectal cancer research nowadays is to understand the development of acquired resistance to anti-EGFR drugs. The key reason for this problem is the KRAS mutations produced after...

    Sheema Sameen, Roberto Barbuti, Paolo Milazzo in Software Engineering and Formal Methods (2015)

  11. No Access

    Chapter and Conference Paper

    Modelling Population Dynamics Using Grid Systems

    A new formalism, Grid Systems, aimed at modelling population dynamics is presented. The formalism is inspired by concepts of Membrane Computing (P Systems) and spatiality dynamics of Cellular Automata. The semant...

    Roberto Barbuti, Antonio Cerone in Information Technology and Open Source: Ap… (2014)

  12. No Access

    Chapter and Conference Paper

    A Computational Formal Model of the Invasiveness of Eastern Species in European Water Frog Populations

    European water frog populations are mainly composed by two species: Pelophylax lessonae (pool frog) and Pelophylax esculentus (edible frog). These populations are called L-E complexes. Edible frogs are a hybrid f...

    Roberto Barbuti, Pasquale Bove in Software Engineering and Formal Methods (2014)

  13. No Access

    Chapter and Conference Paper

    Simulation of Kohn’s Molecular Interaction Maps through Translation into Stochastic CLS+

    Kohn’s Molecular Interaction Maps (MIMs) are a graphical notation for describing bioregulatory networks at the molecular level. Even if the meaning of Kohn’s diagrams can be often easily understood, in many ca...

    Roberto Barbuti, Daniela Lepri in Perspectives of Systems Informatics (2010)

  14. No Access

    Chapter and Conference Paper

    The Calculus of Loo** Sequences

    We describe the Calculus of Loo** Sequences (CLS) which is suitable for modeling microbiological systems and their evolution. We present two extensions, CLS with links (LCLS) and Stochastic CLS. LCLS simplif...

    Roberto Barbuti, Giulio Caravagna in Formal Methods for Computational Systems B… (2008)

  15. Chapter and Conference Paper

    Modeling Long–Running Transactions with Communicating Hierarchical Timed Automata

    Long-running transactions consist of tasks which may be executed sequentially and in parallel, may contain sub-tasks, and may require to be completed before a deadline. These transactions are not atomic and, i...

    Ruggero Lanotte, Andrea Maggiolo-Schettini in Formal Methods for Open Object-Based Distr… (2006)

  16. No Access

    Chapter and Conference Paper

    Bisimulation Congruences in the Calculus of Loo** Sequences

    The Calculus of Loo** Sequences (CLS) is a calculus suitable to describe biological systems and their evolution. CLS terms are constructed by starting from basic constituents and composing them by means of o...

    Roberto Barbuti, Andrea Maggiolo-Schettini in Theoretical Aspects of Computing - ICTAC 2… (2006)