Skip to main content

and
  1. No Access

    Article

    Generalized contexts for reaction systems: definition and study of dynamic causalities

    Reaction systems are a qualitative formalism for the modelling of systems of biochemical reactions. In their original formulation, a reaction system executes in an environment (or context) that c...

    Roberto Barbuti, Roberta Gori, Francesca Levi, Paolo Milazzo in Acta Informatica (2018)

  2. No Access

    Chapter and Conference Paper

    An Algorithm for Simulating Human Selective Attention

    The brain mechanism of selective attention plays a key role in determining the success of a human’s interaction with a device. If the user has to perform concurrent tasks by interacting simultaneously with more t...

    Giovanna Broccia, Paolo Milazzo in Software Engineering and Formal Methods (2018)

  3. No Access

    Chapter and Conference Paper

    A Computational Model of Internet Addiction Phenomena in Social Networks

    Addiction is a complex phenomenon, stemming from environmental, biological and psychological causes. It is defined as a natural response of the body to external stimuli, such as drugs, alcohol, but also job, l...

    Lucia Nasti, Paolo Milazzo in Software Engineering and Formal Methods (2018)

  4. No Access

    Chapter and Conference Paper

    Multiset Patterns and Their Application to Dynamic Causalities in Membrane Systems

    In this paper we investigate dynamic causalities in membrane systems by proposing the concept of “predictor”, originally defined in the context of Ehrenfeucht and Rozemberg’s reaction systems. The goal is to c...

    Roberto Barbuti, Roberta Gori, Paolo Milazzo in Membrane Computing (2018)

  5. No Access

    Chapter and Conference Paper

    Formalizing a Notion of Concentration Robustness for Biochemical Networks

    The main goal of systems biology is to understand the dynamical properties of biological systems by investigating the interactions among the components of a biological system. In this work, we focus on the rob...

    Lucia Nasti, Roberta Gori, Paolo Milazzo in Software Technologies: Applications and Fo… (2018)

  6. No Access

    Chapter and Conference Paper

    Applications of P Systems in Population Biology and Ecology: The Cases of MPP and APP Systems

    We describe two extensions of P systems for the modelling of populations and ecosystems. They are the Minimal Probabilistic P systems (MPP systems) and the Attributed Probabilistic P systems (APP systems). We ...

    Roberto Barbuti, Pasquale Bove, Paolo Milazzo, Giovanni Pardini in Membrane Computing (2017)

  7. No Access

    Book and Conference Proceedings

    Software Technologies: Applications and Foundations

    STAF 2016 Collocated Workshops: DataMod, GCM, HOFM, MELO, SEMS, VeryComp, Vienna Austria, July 4-8, 2016, Revised Selected Papers

    Paolo Milazzo, Dániel Varró in Lecture Notes in Computer Science (2016)

  8. No Access

    Chapter and Conference Paper

    A High-Level Model Checking Language with Compile-Time Pruning of Local Variables

    Among Model Checking tools, the behaviour of a system is often formalized as a transition system with atomic propositions associated with states (Kripke structure). In current modelling languages, transitions are...

    Giovanni Pardini, Paolo Milazzo in Software Technologies: Applications and Foundations (2016)

  9. No Access

    Chapter and Conference Paper

    A Mathematical Model for Assessing KRAS Mutation Effect on Monoclonal Antibody Treatment of Colorectal Cancer

    The most challenging task in colorectal cancer research nowadays is to understand the development of acquired resistance to anti-EGFR drugs. The key reason for this problem is the KRAS mutations produced after...

    Sheema Sameen, Roberto Barbuti, Paolo Milazzo in Software Engineering and Formal Methods (2015)

  10. No Access

    Chapter and Conference Paper

    A Computational Formal Model of the Invasiveness of Eastern Species in European Water Frog Populations

    European water frog populations are mainly composed by two species: Pelophylax lessonae (pool frog) and Pelophylax esculentus (edible frog). These populations are called L-E complexes. Edible frogs are a hybrid f...

    Roberto Barbuti, Pasquale Bove in Software Engineering and Formal Methods (2014)

  11. No Access

    Chapter and Conference Paper

    A Compositional Semantics of Reaction Systems with Restriction

    Reaction systems are an abstract model of interactions among biochemical reactions, developed around two opposite mechanisms: facilitation and inhibition. The evolution of a Reaction System is driven by the ex...

    Giovanni Pardini, Roberto Barbuti in The Nature of Computation. Logic, Algorith… (2013)

  12. No Access

    Chapter and Conference Paper

    Simulation of Kohn’s Molecular Interaction Maps through Translation into Stochastic CLS+

    Kohn’s Molecular Interaction Maps (MIMs) are a graphical notation for describing bioregulatory networks at the molecular level. Even if the meaning of Kohn’s diagrams can be often easily understood, in many ca...

    Roberto Barbuti, Daniela Lepri in Perspectives of Systems Informatics (2010)

  13. No Access

    Chapter and Conference Paper

    Probabilistic Model Checking of Biological Systems with Uncertain Kinetic Rates

    We present an abstraction of the probabilistic semantics of Multiset Rewriting to formally express systems of reactions with uncertain kinetic rates. This allows biological systems modelling when the exact rat...

    Roberto Barbuti, Francesca Levi, Paolo Milazzo, Guido Scatena in Reachability Problems (2009)

  14. No Access

    Chapter and Conference Paper

    The Calculus of Loo** Sequences

    We describe the Calculus of Loo** Sequences (CLS) which is suitable for modeling microbiological systems and their evolution. We present two extensions, CLS with links (LCLS) and Stochastic CLS. LCLS simplif...

    Roberto Barbuti, Giulio Caravagna in Formal Methods for Computational Systems B… (2008)

  15. Chapter and Conference Paper

    Modeling Long–Running Transactions with Communicating Hierarchical Timed Automata

    Long-running transactions consist of tasks which may be executed sequentially and in parallel, may contain sub-tasks, and may require to be completed before a deadline. These transactions are not atomic and, i...

    Ruggero Lanotte, Andrea Maggiolo-Schettini in Formal Methods for Open Object-Based Distr… (2006)

  16. No Access

    Chapter and Conference Paper

    Bisimulation Congruences in the Calculus of Loo** Sequences

    The Calculus of Loo** Sequences (CLS) is a calculus suitable to describe biological systems and their evolution. CLS terms are constructed by starting from basic constituents and composing them by means of o...

    Roberto Barbuti, Andrea Maggiolo-Schettini in Theoretical Aspects of Computing - ICTAC 2… (2006)