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  1. Article

    Open Access

    A survey of gene regulatory networks modelling methods: from differential equations, to Boolean and qualitative bioinspired models

    Gene Regulatory Networks (GRNs) represent the interactions among genes regulating the activation of specific cell functionalities, such as reception of (chemical) signals or reaction to environmental changes. ...

    Roberto Barbuti, Roberta Gori, Paolo Milazzo, Lucia Nasti in Journal of Membrane Computing (2020)

  2. No Access

    Chapter and Conference Paper

    Applications of P Systems in Population Biology and Ecology: The Cases of MPP and APP Systems

    We describe two extensions of P systems for the modelling of populations and ecosystems. They are the Minimal Probabilistic P systems (MPP systems) and the Attributed Probabilistic P systems (APP systems). We ...

    Roberto Barbuti, Pasquale Bove, Paolo Milazzo, Giovanni Pardini in Membrane Computing (2017)

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    Chapter and Conference Paper

    Attributed Probabilistic P Systems and Their Application to the Modelling of Social Interactions in Primates

    We propose a variant of probabilistic P Systems, Attributed Probabilistic P systems (APP systems), in which objects are annotated with attributes. We use APP systems for modelling social behaviours of some spe...

    Roberto Barbuti, Alessandro Bompadre in Software Engineering and Formal Methods (2015)

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    Chapter and Conference Paper

    A Tool for the Modelling and Simulation of Ecological Systems Based on Grid Systems

    Grid Systems is a formalism for modelling population and ecosystem dynamics that combines features of membrane computing, such as rewrite rules and maximal parallelism, with a representation of space similar t...

    Suryana Setiawan, Antonio Cerone, Paolo Milazzo in Software Engineering and Formal Methods (2015)

  5. No Access

    Chapter

    Systolic Automata and P Systems

    Systolic automata are models of highly-concurrent language acceptors based on identical processors with one-way flow of information, amenable to efficient hardware implementation as multiprocessor chips.

    Roberto Barbuti, Andrea Maggiolo-Schettini, Paolo Milazzo in Computing with New Resources (2014)

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    Chapter and Conference Paper

    A Compositional Semantics of Reaction Systems with Restriction

    Reaction systems are an abstract model of interactions among biochemical reactions, developed around two opposite mechanisms: facilitation and inhibition. The evolution of a Reaction System is driven by the ex...

    Giovanni Pardini, Roberto Barbuti in The Nature of Computation. Logic, Algorith… (2013)

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    Chapter and Conference Paper

    Membrane Systems Working in Generating and Accepting Modes: Expressiveness and Encodings

    Membrane systems can be seen either as generators or as acceptors of multiset languages. In this paper we compare the expressive power of membrane systems working in accepting mode with that of membrane system...

    Roberto Barbuti, Andrea Maggiolo-Schettini, Paolo Milazzo in Membrane Computing (2011)

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    Chapter

    Delay Stochastic Simulation of Biological Systems: A Purely Delayed Approach

    Delays in biological systems may be used to model events for which the underlying dynamics cannot be precisely observed. Mathematical modeling of biological systems with delays is usually based on Delay Differ...

    Roberto Barbuti, Giulio Caravagna in Transactions on Computational Systems Biol… (2011)

  9. No Access

    Chapter and Conference Paper

    Probabilistic Model Checking of Biological Systems with Uncertain Kinetic Rates

    We present an abstraction of the probabilistic semantics of Multiset Rewriting to formally express systems of reactions with uncertain kinetic rates. This allows biological systems modelling when the exact rat...

    Roberto Barbuti, Francesca Levi, Paolo Milazzo, Guido Scatena in Reachability Problems (2009)

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    Chapter and Conference Paper

    Stochastic Calculus of Loo** Sequences for the Modelling and Simulation of Cellular Pathways

    The paper presents the Stochastic Calculus of Loo** Sequences (SCLS) suitable to describe microbiological systems, such as cellular pathways, and their evolution. Systems are represented by terms. The terms ...

    Roberto Barbuti, Andrea Maggiolo-Schettini in Transactions on Computational Systems Biol… (2008)

  11. No Access

    Chapter and Conference Paper

    The Calculus of Loo** Sequences for Modeling Biological Membranes

    We survey the formalism Calculus of Loo** Sequences (CLS) and a number of its variants from the point of view of their use for describing biological membranes. The CLS formalism is based on term rewriting an...

    Roberto Barbuti, Andrea Maggiolo–Schettini, Paolo Milazzo in Membrane Computing (2007)

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    Chapter and Conference Paper

    Bisimulation Congruences in the Calculus of Loo** Sequences

    The Calculus of Loo** Sequences (CLS) is a calculus suitable to describe biological systems and their evolution. CLS terms are constructed by starting from basic constituents and composing them by means of o...

    Roberto Barbuti, Andrea Maggiolo-Schettini in Theoretical Aspects of Computing - ICTAC 2… (2006)